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PRJNA240307 SRP040146

Fecal Microbiota Transplant for C. diff, USA

C.diff FMT

127 gut samples from a US study of fecal microbiota transplant (FMT) for C. difficile, with an "other" study design; no demographic or health-condition details provided. machine-written summary

127 samples · 2,133 runs · US · Age unknown · 2014 · 9.01 Gbp / sample

Sources
✓Sequence archive 127○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive127 sample values (country)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC9426582
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

Faecal microbiota transplantation · population gi_infection_or_diarrhoea · FMT for C. difficile infection

“C.diff FMT” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 country
Age
unknown127
Country
US127
Body site
primary127
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 4 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 81 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 41 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 9.01 Gbp per sample0130Gbp
Sampling design and relatedness

FMT donor → recipient — not resolved

FMT (fecal microbiota transplant) study for C. diff; donor-recipient relationship implied by title/description.

How longitudinal and relatedness information is derived

Community composition
Prevotella 7.5%Escherichia 5.3%Streptococcus 4.4%Bacteroides 4.4%Blautia_A 3.9%Klebsiella 3.8%Phocaeicola 3.5%Faecalibacterium 3.0%Akkermansia 2.8%Bifidobacterium 2.6%Roseburia 2.4%Enterococcus_B 2.3%not assigned to a genus 13.4%other genera 40.6%

Genera, mean relative abundance over 124 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country127 100%127
health_condition0 0%
subject_id0 0%
Papers (1)
Details
Archive description

C.diff FMT

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN02675497countryUSR10.90sample.attr.geo_loc_nameUSA
Sequencing

2,133 runs over 127 samples · mean 0.63 Gbp per run (median 0.41 Gbp, total 1,352.44 Gbp; 2,133 runs with a base count) · layout PAIRED 2,133 · platform ILLUMINA 2,133 · models Illumina HiSeq 2000 (2,133) · 87% of runs with a Sandpiper profile · first public 2014-03-18 – 2014-08-11

Authors (9)

Wandro S first · Ghatbale P · Attai H · Hendrickson C · Samillano C · Suh J · Dunham SJB · Pride DT · Whiteson K last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA240307.csv.gz (3.7 KB) · parquet (73.3 KB) — all 127 samples, every field with route and confidence · PRJNA240307_determinations.csv.gz (711 B) — 127 evidence rows

Samples (127 · every field this project has values for · hover a cell for its source)
Loading the sample table…