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PRJNA299502 SRP066053

Gut microbiome in Cheyenne & Arapaho vs Oklahoma non-natives

Human Gut Microbiome Metagenome

37 fecal samples from Cheyenne and Arapaho and non-native individuals in Oklahoma, comparing gut microbiome diversity between type 2 diabetes (19) and healthy controls (18) in a case-control design. machine-written summary

37 samples · 37 runs · US · Age unknown · 2015 · 4.31 Gbp / sample

Sources
✓Sequence archive 74○Abstract / description○Full text○Supplementary tables✓External resources 222–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive74 sample values (country, location region)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC11009399, PMC13059687, PMC4703035, PMC6961876, PMC8325300
○ Supplementary tablesfiles read; no table could be matched to the samples
✓ External resources222 sample values (age, antibiotic exposure, bmi, health condition, health condition detail, sex) · from curatedMetagenomicData 3 (cMD 3)
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult29
elderly5
unknown3
Condition
type2_diabetes19
healthy_control18
Sex
female23
male14
Country
US37
Body site
primary37
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 2 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 35 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.31 Gbp per sample0130Gbp
Community composition
Faecalibacterium 8.7%Roseburia 7.0%Blautia_A 5.8%Mediterraneibacter 5.6%Ruminococcoides 4.2%Prevotella 3.6%Bacteroides 3.5%Phocaeicola 3.3%Vescimonas 2.3%Fimenecus 2.1%Bifidobacterium 2.0%Streptococcus 1.9%not assigned to a genus 5.1%other genera 44.9%

Genera, mean relative abundance over 30 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category34 92%
country37 100%37
health_condition37 100%37
subject_id0 0%
age_at_collection_days37 100%37
antibiotic_exposure37 100%37
bmi37 100%37
detailed_location37 100%
health_condition_detail37 100%37
location_region37 100%37
sex37 100%37
Papers (6)
  • Gut Microbiome Diversity among Cheyenne and Arapaho Individuals from Western Oklahoma. 2015 PMID 26671671 PMC4703035 own_data
  • Biogeographic study of human gut-associated crAssphage suggests impacts from industrialization and recent expansion. 2020 PMID 31940321 PMC6961876 unsure
  • HumGut: a comprehensive human gut prokaryotic genomes collection filtered by metagenome data. 2021 PMID 34330336 PMC8325300 unsure
  • Plasmids in the human gut reveal neutral dispersal and recombination that is overpowered by inflammatory diseases. 2024 PMID 38605009 PMC11009399 unsure
  • Gut bacteria metabolize natural and synthetic steroid hormones via the reductive OsrABC pathway. 2025 PMID 41118772 PMC13059687 unsure
1 more
  • Plasmid dispersal and recombination across human gut microbiomes is neutral, but overpowered by inflammatory diseases 2023
Details
Archive description

Gut microbiome diversity among the Cheyenne &amp Arapaho of Oklahoma

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN04209218age_at_collection_days20088.75R20.75external.cmd sourceage: 55; age_unit: Year; age_group: Adult
SAMN04209218antibiotic_exposureyesR20.75external.cmd sourceantibiotics_current_use: Yes
SAMN04209218bmi31.0R20.75external.cmd sourcebmi: 31
SAMN04209218countryUSR10.90sample.attr.geo_loc_nameUSA: Oklahoma
SAMN04209218health_conditionhealthy_controlR20.75external.cmd sourcedisease: Healthy
SAMN04209218health_condition_detailHealthyR20.75external.cmd sourcedisease: Healthy
SAMN04209218location_regionOklahomaR10.85biosample.attribute:geo_loc_nameUSA: Oklahoma
SAMN04209218sexmaleR20.75external.cmd sourcesex: Male
Sequencing

37 runs over 37 samples · mean 4.32 Gbp per run (median 4.31 Gbp, total 159.87 Gbp; 37 runs with a base count) · layout PAIRED 37 · platform ILLUMINA 37 · models Illumina HiSeq 2000 (37) · 81% of runs with a Sandpiper profile · first public 2015-12-05

Authors (71)

Sankaranarayanan K first · Ozga AT · Warinner C · Tito RY · Obregon-Tito AJ · Xu J · Gaffney PM · Jervis LL · Cox D · Stephens L · Foster M · Tallbull G · Spicer P · Lewis CM last · Honap TP first · Schnorr SL · Ormaasen I first · Rudi K · Diep DB · Snipen L last · Levy S · Arp G · Zhong A · Ndjite GM · Weiss A · Braccia D · Jenkins C · Grant MR · Abeysinghe S · Yang Y · Jermain MD · Wu CH · Ma B · Argentini C first · Lugli GA · Tarracchini C · Fontana F · Mancabelli L · Viappiani A · Anzalone R · Angelini L · Alessandri G · Longhi G · Bianchi MG · Taurino G · Bussolati O · Milani C · van Sinderen D · Turroni F · Ventura M last · Zorea A first · Pellow D · Levin L · Pilosof S · Friedman J · Shamir R · Mizrahi I last · Jacoby C first · Scorza K · Ecker L · Nol Bernardino P · Little AS · McMillin M · Ramaswamy R · Sundararajan A · Sidebottom AM · Lin H · Dufault-Thompson K · Hall B · Jiang X · Light SH last

Downloads

PRJNA299502.csv.gz (2.2 KB) · parquet (71.3 KB) — all 37 samples, every field with route and confidence · PRJNA299502_determinations.csv.gz (4.1 KB) — 296 evidence rows

Samples (37 · every field this project has values for · hover a cell for its source)
Loading the sample table…