Gut microbiome before/after simulated space capsule, Beijing
Longitudinal study of 4 fecal samples from two male crewmembers in Beijing, China, collected before and after a 33-day high-fidelity ground simulation of a space capsule, examining effects on gut microbiota diversity and abundance. machine-written summary
4 samples · 4 runs · CN · Adult · 2017 · 6.22 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 48 sample values (age, collection date, country, health condition, health condition detail, latitude, location locality, location region) |
| ✓ Abstract / description | 8 sample values (lifestyle, lifestyle detail) |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Other administered intervention (see intervention_detail) design single_arm_before_after · population healthy_control · Simulated 33-day space capsule confinement, sampled before and after
“lived in a high-fidelity ground simulation of a space capsule” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal
2 of 2 people sampled more than once (4 samples; median 2, up to 2 per person) · follow-up median 33 d (max 33 d) · median interval between samples 33 d (time from collection dates).
Each row is one person (2 shown); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 4 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 4 | 100% | ||||
| country | 4 | 100% | 4 | |||
| health_condition | 4 | 100% | 4 | |||
| subject_id | 4 | 100% | 4 | |||
| age_at_collection_days | 4 | 100% | 4 | |||
| collection_date | 4 | 100% | 4 | |||
| detailed_location | 4 | 100% | ||||
| health_condition_detail | 4 | 100% | 4 | |||
| latitude | 4 | 100% | 4 | |||
| lifestyle | 4 | 100% | 4 | |||
| lifestyle_detail | 4 | 100% | 4 | |||
| location_locality | 4 | 100% | 4 | |||
| location_region | 4 | 100% | 4 | |||
| longitude | 4 | 100% | 4 | |||
| sex | 4 | 100% | 4 | |||
| timepoint_label | 4 | 100% | 4 |
Archive description
There are four Metagenome Sequences in this project, which are FS.A0, FS.B0, FS.A33 and FS.B33. Two male crewmembers (A and B) lived in a high-fidelity ground simulation of a space capsule for 33 days. The fresh fecal samples were collected before and just after the simulation (FS.0 and FS.33). Metagenomic approaches were used to investigate the influence of living in a simulated space capsule on the diversity and abundance of the gut microbiota.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “The gut microbiome before and”
- body site study.description · “days. The fresh fecal samples were collected”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN06046216 | age_at_collection_days | 12784.0 | R1 | 0.90 | sample.attr.host_age | 35y |
| SAMN06046216 | collection_date | 2015-05-08 | R1 | 0.90 | biosample.attribute:collection_date | 2015-05-08 |
| SAMN06046216 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China:Beijing |
| SAMN06046216 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:gastrointest_disord | no gastrointestinal disorder |
| SAMN06046216 | health_condition_detail | no liver disorder | R1 | 0.90 | sample.attr.liver_disord | no liver disorder |
| SAMN06046216 | latitude | 40.0400 | R1 | 0.90 | biosample.attribute:lat_lon | 40.04 N 116.15 E |
| SAMN06046216 | lifestyle | spaceflight_or_analog | R4 | 0.40 | ena.study_title | simulated space capsule life |
| SAMN06046216 | lifestyle_detail | Space-analog capsule simulation crewmembers | R4 | 0.40 | ena.study_title | simulated space capsule life |
| SAMN06046216 | location_locality | Beijing | R1 | 0.85 | biosample.attribute:geo_loc_name | China:Beijing |
| SAMN06046216 | location_region | Beijing | R1 | 0.60 | biosample.attribute:lat_lon | 40.04 N 116.15 E |
| SAMN06046216 | longitude | 116.1500 | R1 | 0.90 | biosample.attribute:lat_lon | 40.04 N 116.15 E |
| SAMN06046216 | sex | male | R1 | 0.90 | sample.attr.host_sex | male |
| SAMN06046216 | subject_id | A | R1 | 0.70 | sample.name_rule:library_names | A0 |
| SAMN06046216 | timepoint_label | 0 | R1 | 0.70 | sample.name_rule:library_names | A0 |
Sequencing
4 runs over 4 samples · mean 6.39 Gbp per run (median 6.22 Gbp, total 25.55 Gbp; 4 runs with a base count) · layout PAIRED 4 · platform ILLUMINA 4 · models Illumina HiSeq 2500 (4) · 100% of runs with a Sandpiper profile · first public 2017-01-16
Authors (24)
Argentini C first · Lugli GA · Tarracchini C · Fontana F · Mancabelli L · Viappiani A · Anzalone R · Angelini L · Alessandri G · Longhi G · Bianchi MG · Taurino G · Bussolati O · Milani C · van Sinderen D · Turroni F · Ventura M last · De Biase R · Bocchio F · De Conto F · Nouvenne A · Ticinesi A · Meschi T · Cecchi R
Downloads
PRJNA360177.csv.gz (1.1 KB) · parquet (71.5 KB) — all 4 samples, every field with route and confidence · PRJNA360177_determinations.csv.gz (1.3 KB) — 56 evidence rows