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PRJNA381333 SRP103054

Tibetan plateau gut microbiota, cross-sectional 16S study

Tibetan Gut Miicrobiota Metagenome

208 gut microbiota samples from healthy individuals across six locations in China (Gannan, Naqu, Lhasa, Hongyuan, Gangcha, Tianzhu), spanning infant to elderly age groups, in a cross-sectional study of high-altitude adaptation. machine-written summary

208 samples · 208 runs · CN · Adult · 2018 · 41.8 Mbp / sample

Sources
✓Sequence archive 1,434○Abstract / description✓Full text 624○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,434 sample values (age, collection date, country, latitude, location locality, location region, longitude, sex)
○ Abstract / descriptionread; no usable statement
✓ Full text624 sample values (antibiotic exposure, health condition, health condition detail) · PMC10696028, PMC11086029
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
6 sampling locations · 1 country
Age
adult140
elderly25
child23
adolescent11
infant9
Condition
healthy_control208
Sex
female113
male95
Country
CN208
Body site
primary208
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 14 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 194 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.04 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category208 100%
country208 100%208
health_condition208 100%208
subject_id0 0%
age_at_collection_days208 100%208
antibiotic_exposure208 100%208
collection_date208 100%208
health_condition_detail208 100%208
latitude208 100%208
longitude208 100%208
sex208 100%208
detailed_location156 75%
location_locality156 75%156
location_region30 14%30
Papers (2)
  • Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation. 2024 PMID 38715346 PMC11086029 own_data
  • Gut microbiomes of agropastoral children from the Adadle region of Ethiopia reflect their unique dietary habits. 2023 PMID 38049420 PMC10696028 unsure
Details
Archive description

Description the characteristics of Tibetan gut miicrobiota

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult and child and elderly by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.scientific_name · “human gut metagenome(208)”
  • body site study.title · “Tibetan Gut Miicrobiota Metagenome”
  • life stage sample.attr.host_age · “23 (n=137/208)”
  • life stage sample.attr.host_age · “4 (n=28/208)”
  • life stage sample.attr.host_age · “72 (n=23/208)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN06674726age_at_collection_days18262.5R10.70sample.attr.host_age50
SAMN06674726antibiotic_exposurenoR30.70paper.fulltext.methodshad not taken antibiotics within the 3 months before sampling
SAMN06674726collection_date2015-10-10R10.90biosample.attribute:collection_date2015-10-10
SAMN06674726countryCNR10.90sample.attr.geo_loc_nameChina:Hongyuan
SAMN06674726health_conditionhealthy_controlR30.70paper.fulltext.methodsfree of diseases and had not taken antibiotics
SAMN06674726health_condition_detailfree of diseasesR30.70paper.fulltext.methodsfree of diseases and had not taken antibiotics
SAMN06674726latitude31.5100R10.90biosample.attribute:lat_lon31.51 N 101.51 E
SAMN06674726location_localityHongyuanR10.85biosample.attribute:geo_loc_nameChina:Hongyuan
SAMN06674852location_regionGansu ShengR10.60biosample.attribute:lat_lon36.98 N 103.13 E
SAMN06674726longitude101.5100R10.90biosample.attribute:lat_lon31.51 N 101.51 E
SAMN06674726sexfemaleR10.90sample.attr.host_sexfemale
Sequencing

208 runs over 208 samples · mean 41.4 Mbp per run (median 41.8 Mbp, total 8.61 Gbp; 208 runs with a base count) · layout PAIRED 208 · platform ILLUMINA 208 · models Illumina MiSeq (208) · 0% of runs with a Sandpiper profile · first public 2018-04-06

Authors (19)

Yersin S first · Garneau JR · Schneeberger PHH · Osman KA · Cercamondi CI · Muhummed AM · Tschopp R · Zinsstag J · Vonaesch P last · Zhao H first · Sun L · Liu J · Shi B · Zhang Y · Qu-Zong CR · Dorji T · Wang T · Yuan H · Yang J last

Downloads

PRJNA381333.csv.gz (6.2 KB) · parquet (79.2 KB) — all 208 samples, every field with route and confidence · PRJNA381333_determinations.csv.gz (12.3 KB) — 2,058 evidence rows

Samples (208 · every field this project has values for · hover a cell for its source)
Loading the sample table…