Gut microbiota in functional constipation vs healthy, Italy
Case-control shotgun metagenomic study of 10 stool samples from Italian adults (5 with functional constipation, 5 healthy controls), comparing gut microbial metabolic pathways between groups. machine-written summary
10 samples · 10 runs · IT · Adult · 2018 · 2.00 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 49 sample values (collection date, country, health condition, health condition detail, subject id) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC5575163 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Genera, mean relative abundance over 8 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 10 | 100% | ||||
| country | 10 | 100% | 10 | |||
| health_condition | 10 | 100% | 10 | |||
| subject_id | 9 | 90% | 9 | |||
| collection_date | 10 | 100% | 10 | |||
| health_condition_detail | 10 | 100% | 10 |
- Unveiling the gut microbiota composition and functionality associated with constipation through metagenomic analyses. 2017 PMID 28852182 PMC5575163 own_data
Archive description
Unveiling the gut microbiota composition and functionality associated with constipation through metagenomic analyses - metagenome
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Unveiling the gut microbiota composition and”
- body site study.description · “Unveiling the gut microbiota composition and”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN06947071 | collection_date | 2016-01-01 | R1 | 0.90 | biosample.attribute:collection_date | 2016-01-01 |
| SAMN06947071 | country | IT | R1 | 0.90 | sample.attr.geo_loc_name | Italy |
| SAMN06947071 | health_condition | other_disease | R1 | 0.70 | sample.name_rule:library_name | FC_S_65 |
| SAMN06947071 | health_condition_detail | FC | R1 | 0.70 | sample.name_rule:library_name | FC_S_65 |
| SAMN06947071 | subject_id | 65 | R1 | 0.70 | sample.name_rule:library_name | FC_S_65 |
Sequencing
10 runs over 10 samples · mean 1.88 Gbp per run (median 2.00 Gbp, total 18.79 Gbp; 10 runs with a base count) · layout PAIRED 10 · platform ILLUMINA 10 · models NextSeq 500 (10) · 80% of runs with a Sandpiper profile · first public 2018-11-22
Authors (19)
Mancabelli L first · Milani C · Lugli GA · Turroni F · Mangifesta M · Viappiani A · Ticinesi A · Nouvenne A · Meschi T · van Sinderen D · Ventura M last · Tarracchini C first · Fontana F · Alessandri G · De Biase R · Bocchio F · De Conto F · Bussolati O · Cecchi R
Downloads
PRJNA386422.csv.gz (1.2 KB) · parquet (69.6 KB) — all 10 samples, every field with route and confidence · PRJNA386422_determinations.csv.gz (966 B) — 49 evidence rows