Home › Studies › PRJNA421881
PRJNA421881 SRP126540

Gut metagenome of vegetarians, vegans, omnivores in Italy

human gut metagenome Metagenome

Cross-sectional study of 74 human gut metagenome samples from healthy adults in Italy, comparing vegetarian, vegan, and omnivore diets. machine-written summary

74 samples · 74 runs · IT · Age unknown · 2017 · 10.34 Gbp / sample

Sources
✓Sequence archive 222○Abstract / description○Full text○Supplementary tables✓External resources 370–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive222 sample values (collection date, country, diet)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC12390848, PMC12940152, PMC13098223, PMC8325300, PMC8634118
○ Supplementary tablesfiles read; no table could be matched to the samples
✓ External resources370 sample values (age, bmi, health condition, health condition detail, sex) · from curatedMetagenomicData 3 (cMD 3)
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult74
Condition
healthy_control74
Sex
male38
female36
Country
IT74
Body site
primary74
Collected 2013–2017
2013: 14 samples2014: 15 samples2017: 45 samples20132017
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 1 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 34 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 39 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.34 Gbp per sample0130Gbp
Community composition
Prevotella 19.6%Faecalibacterium 10.1%Alistipes 6.0%Gemmiger 4.2%Bifidobacterium 3.6%Vescimonas 3.0%Phocaeicola 2.4%Bacteroides 2.0%Hominicoprocola 1.8%Roseburia 1.5%Sutterella 1.5%Ruminococcoides 1.4%not assigned to a genus 4.1%other genera 38.7%

Genera, mean relative abundance over 67 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category74 100%
country74 100%74
health_condition74 100%74
subject_id0 0%
age_at_collection_days74 100%74
bmi74 100%74
collection_date74 100%74
diet74 100%74
health_condition_detail74 100%74
sex74 100%74
Papers (5)
  • HumGut: a comprehensive human gut prokaryotic genomes collection filtered by metagenome data. 2021 PMID 34330336 PMC8325300 unsure
  • A versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems. 2021 PMID 34676563 PMC8634118 unsure
  • Microbiota-driven antitumour immunity mediated by dendritic cell migration. 2025 PMID 40659786 PMC12390848 unsure
  • Landscape of flavonoid metabolism in human gut microbiome and its association with health and disease. 2025 PMID 41909884 PMC12940152 unsure
  • The chicken gut virome: spatial structuring and extensive diversity of 19,778 viral populations. 2026 PMID 41910132 PMC13098223 unsure
Details
Archive description

human gut metagenome of vegetarians, vegans and omnivores

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “human gut metagenome Metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN08159961age_at_collection_days19358.25R20.75external.cmd sourceage: 53; age_unit: Year; age_group: Adult
SAMN08159961bmi20.3R20.75external.cmd sourcebmi: 20.3
SAMN08159961collection_date2013R10.90biosample.attribute:collection_date2013
SAMN08159961countryITR10.90sample.attr.geo_loc_nameItaly
SAMN08159961dietvegetarianR10.85biosample.attribute:attributeattribute: 04.TO.VG
SAMN10285266dietomnivoreR10.70sample.name_rule:DESCRIPTIONDESCRIPTION: gut metagenome of omnivore subject from Bari (Italy), subject ID 03BA
SAMN08159961health_conditionhealthy_controlR20.75external.cmd sourcedisease: Healthy
SAMN08159961health_condition_detailHealthyR20.75external.cmd sourcedisease: Healthy
SAMN08159961sexmaleR20.75external.cmd sourcesex: Male
Sequencing

74 runs over 74 samples · mean 10.29 Gbp per run (median 10.34 Gbp, total 761.77 Gbp; 74 runs with a base count) · layout PAIRED 74 · platform ILLUMINA 74 · models NextSeq 500 (74) · 91% of runs with a Sandpiper profile · first public 2017-12-13 – 2018-11-10

Authors (76)

Hiseni P first · Rudi K · Wilson RC · Hegge FT · Snipen L last · Li J first · Gálvez EJC · Amend L · Almási · Iljazovic A · Lesker TR · Bielecka AA · Schorr EM · Strowig T last · Argentini C first · Lugli GA · Tarracchini C · Fontana F · Mancabelli L · Viappiani A · Anzalone R · Angelini L · Alessandri G · Longhi G · Bianchi MG · Taurino G · Bussolati O · Milani C · van Sinderen D · Turroni F · Ventura M last · Lin NY first · Fukuoka S · Koyama S · Motooka D · Tourlousse DM · Shigeno Y · Matsumoto Y · Yamano H · Murotomi K · Tamaki H · Irie T · Sugiyama E · Kumagai S · Itahashi K · Tanegashima T · Fujimaki K · Ito S · Shindo M · Tsuji T · Wake H · Watanabe K · Maeda Y · Enokida T · Tahara M · Yamashita R · Fujisawa T · Nomura M · Kawazoe A · Goto K · Doi T · Shitara K · Mano H · Sekiguchi Y · Nakamura S · Benno Y · Nishikawa H last · Pateriya D first · Prasoodanan P K V · Scaria J · Sharma VK last · Sáenz JS first · Yergaliyev T · Rios-Galicia B · Seifert J · Camarinha-Silva A last

Downloads

PRJNA421881.csv.gz (3.2 KB) · parquet (73.6 KB) — all 74 samples, every field with route and confidence · PRJNA421881_determinations.csv.gz (7.8 KB) — 592 evidence rows

Samples (74 · every field this project has values for · hover a cell for its source)
Loading the sample table…