Gut microbiome in obese adults, water-only fasting, China
211 fecal metagenome samples from obese adults in Haikou and Beijing, China, collected across a 7-day medically supervised water-only fasting intervention to study gut microbiota dynamics. machine-written summary
211 samples · 211 runs · CN · Age unknown · 2019 · 6.18 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,266 sample values (collection date, country, latitude, location locality, longitude, subject id) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 422 sample values (health condition, health condition detail) · PMC10579591 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Controlled / prescribed diet or feeding regimen design single_arm_before_after · population obesity · 7-day medically supervised water-only fasting, 46 obese volunteers
“7-days medically supervised water-only fasting for 46 obese volunteers” — abstract:37854337 (study level; per-sample arms are in the intervention column below)
longitudinal
46 of 46 people sampled more than once (211 samples; median 5, up to 5 per person) · follow-up median 26 d (max 27 d) · median interval between samples 7 d (time from collection dates). Schedule stated by the source: “stool at baseline (T0), day 3 and day 7 during fasting, day 14 and day 21 after fasting” (time origin: intervention_start); stated follow-up 21 d.
Each row is one person (36 shown of 46); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 210 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 211 | 100% | ||||
| country | 211 | 100% | 211 | |||
| health_condition | 211 | 100% | 211 | |||
| subject_id | 211 | 100% | 211 | |||
| collection_date | 211 | 100% | 211 | |||
| detailed_location | 211 | 100% | ||||
| health_condition_detail | 211 | 100% | 211 | |||
| latitude | 211 | 100% | 211 | |||
| location_locality | 211 | 100% | 211 | |||
| longitude | 211 | 100% | 211 |
- Dynamics and ecological reassembly of the human gut microbiome and the host metabolome in response to prolonged fasting. 2023 PMID 37854337 PMC10579591 own_data
Archive description
Dynamics of the human gut microbiome under fasting treatment
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.62. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site study.description · “Dynamics of the human gut microbiome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN08474157 | collection_date | 2016-11-29 | R1 | 0.90 | biosample.attribute:collection_date | 2016-11-29 |
| SAMN08474157 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Haikou |
| SAMN08474157 | health_condition | obesity | R3 | 0.70 | paper.fulltext.abstract | 46 obese volunteers |
| SAMN08474157 | health_condition_detail | 46 obese volunteers | R3 | 0.70 | paper.fulltext.abstract | 46 obese volunteers |
| SAMN08474157 | latitude | 20.1000 | R1 | 0.90 | biosample.attribute:lat_lon | 20.1 N 110.2 E |
| SAMN08474157 | location_locality | Haikou | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Haikou |
| SAMN08474157 | longitude | 110.2000 | R1 | 0.90 | biosample.attribute:lat_lon | 20.1 N 110.2 E |
| SAMN08474157 | subject_id | OF07 | R1 | 0.70 | sample.name_rule:alias | OF07-T0 |
Sequencing
211 runs over 211 samples · mean 6.23 Gbp per run (median 6.18 Gbp, total 1,313.98 Gbp; 211 runs with a base count) · layout PAIRED 211 · platform ILLUMINA 211 · models Illumina HiSeq 2000 (211) · 100% of runs with a Sandpiper profile · first public 2019-10-02
Authors (12)
Sang X first · Li S · Guo R · Yan Q · Liu C · Zhang Y · Lv Q · Wu L · Ma J · You W · Feng L · Sun W last
Downloads
PRJNA433058.csv.gz (6.1 KB) · parquet (77.7 KB) — all 211 samples, every field with route and confidence · PRJNA433058_determinations.csv.gz (11.3 KB) — 1,688 evidence rows