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PRJNA451097 SRP161684

Gut microbiota, metabolic syndrome in elderly, Austria

Metagenome shotgun sequencing of human gut microbiota and metabolic syndrome

Cross-sectional shotgun metagenomic study of 12 gut microbiome samples from elderly individuals in Salzburg, Austria, examining associations between bacterial community function, gender, and metabolic syndrome. machine-written summary

12 samples · 12 runs · AT · Elderly · 2022 · 12.70 Gbp / sample

Sources
✓Sequence archive 96–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive96 sample values (collection date, country, health condition, health condition detail, latitude, location locality, location region, longitude)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
elderly12
Condition
cardiometabolic_other6
Sex
female6
male6
Country
AT12
Body site
primary12
Collected 2010–2014
2010: 4 samples2013: 5 samples2014: 3 samples20102014
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 11 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 12.70 Gbp per sample0130Gbp
Community composition
Faecalibacterium 8.7%Roseburia 8.1%Bacteroides 4.7%Blautia_A 3.5%Phocaeicola 3.5%Gemmiger 2.9%Lachnospira 2.8%CAG-269 2.6%CAG-273 2.6%DNVW01 2.4%Ruminococcoides 2.4%Prevotella 2.4%not assigned to a genus 3.9%other genera 49.3%

Genera, mean relative abundance over 11 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category12 100%
country12 100%12
health_condition6 50%6
subject_id0 0%
collection_date12 100%12
detailed_location12 100%
latitude12 100%12
location_locality12 100%12
location_region12 100%12
longitude12 100%12
sex12 100%12
health_condition_detail6 50%6
Details
Archive description

The study explores associations between the function of gut bacterial communities on metagenome shotgun sequencing level and gender and the metabolic syndrome in seniors.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of elderly by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome(12)”
  • body site study.title · “human gut microbiota”
  • life stage study.description · “metabolic syndrome in seniors”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN08944456collection_date2010R10.90biosample.attribute:collection_date2010
SAMN08944456countryATR10.90sample.attr.geo_loc_nameAustria: Salzburg
SAMN08944456health_conditioncardiometabolic_otherR10.70sample.name_rule:library_namesSG01fms
SAMN08944456health_condition_detailSG01fmsR10.70sample.name_rule:library_namesSG01fms
SAMN08944456latitude47.8100R10.90biosample.attribute:lat_lon47.81 N 13.10000000 E
SAMN08944456location_localitySalzburgR10.85biosample.attribute:geo_loc_nameAustria: Salzburg
SAMN08944456location_regionSalzburgR10.85biosample.attribute:geo_loc_nameAustria: Salzburg
SAMN08944456longitude13.1000R10.90biosample.attribute:lat_lon47.81 N 13.10000000 E
SAMN08944456sexfemaleR10.70sample.name_rule:library_namesSG01fms
Sequencing

12 runs over 12 samples · mean 12.43 Gbp per run (median 12.70 Gbp, total 149.22 Gbp; 12 runs with a base count) · layout PAIRED 12 · platform ILLUMINA 12 · models Illumina HiSeq 2500 (12) · 92% of runs with a Sandpiper profile · first public 2022-04-20

Authors (0)

No author record.

Downloads

PRJNA451097.csv.gz (1.2 KB) · parquet (70.5 KB) — all 12 samples, every field with route and confidence · PRJNA451097_determinations.csv.gz (1.3 KB) — 96 evidence rows

Samples (12 · every field this project has values for · hover a cell for its source)
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