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PRJNA472785 SRP148806

Athlete Gut Microbiome and Exercise, USA

Athlete Gut Microbiome Metagenomic Sequencing

87 gut metagenome samples from rowers, marathon runners, and sedentary controls in the USA, collected before and after exercise, in an intervention study on exercise-induced changes in the gut microbiome. machine-written summary

87 samples · 87 runs · US · Adult · 2019 · 0.36 Gbp / sample

Sources
✓Sequence archive 426✓Abstract / description 87○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive426 sample values (collection date, country, latitude, location region, longitude)
✓ Abstract / description87 sample values (health condition detail)
○ Full textread; no usable statement or table · PMC11684919, PMC7368972, PMC9045144, PMC9926762
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

Exercise / physical-training programme · population healthy_control · Metagenomic sampling of athletes/sedentary controls before and after exercise/marathon

“rowers, marathon runners, and sedentary controls before and after exercise” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
adult87
Country
US87
Body site
primary87
Collected 2015–2016
2015: 7 samples2016: 71 samples20152016
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 14 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 9 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 14 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 40 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 7 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 2 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 1 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.36 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

Schedule stated by the source: “Samples collected before and after exercise in athletes (rowers, marathon runners) and sedentary controls; exact schedule/timing not detailed numerically.”.

How longitudinal and relatedness information is derived

Community composition
Faecalibacterium 15.7%Prevotella 11.6%Roseburia 9.0%Phocaeicola 5.9%Ruminococcoides 5.7%Bacteroides 4.8%Alistipes 2.3%Lachnospira 2.1%Coprococcus 2.1%Hominimerdicola 1.9%Eubacterium_R 1.8%Ruminococcus_C 1.7%not assigned to a genus 7.0%other genera 28.4%

Genera, mean relative abundance over 9 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category87 100%
country87 100%87
health_condition0 0%
subject_id0 0%
detailed_location87 100%
health_condition_detail87 100%87
latitude87 100%87
location_region87 100%87
longitude87 100%87
collection_date78 90%78
Papers (4)
  • Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. 2019 PMID 31235964 PMC7368972 own_data
  • Investigation of the Ecological Link between Recurrent Microbial Human Gut Communities and Physical Activity. 2022 PMID 35377222 PMC9045144 unsure
  • The human gut microbiome of athletes: metagenomic and metabolic insights. 2023 PMID 36782241 PMC9926762 unsure
  • Cataloging metagenome-assembled genomes and microbial genes from the athlete gut microbiome. 2024 PMID 39741946 PMC11684919 unsure
Details
Archive description

Metagenomic Sequencing of rowers, marathon runners, and sedentary controls before and after exercise.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Athlete Gut Microbiome Metagenomic Sequencing”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN09243345collection_date2016-04-18R10.90biosample.attribute:collection_date2016-04-18
SAMN09243345countryUSR10.90sample.attr.geo_loc_nameUSA
SAMN09243345health_condition_detailmixed_case_control: elite athletes (rowers, marathon runners) vs sedentary controlsR40.50study.descriptionrowers, marathon runners, and sedentary controls
SAMN09243345latitude42.3600R10.90biosample.attribute:lat_lon42.36 N 71.05 W
SAMN09243345location_regionMassachusettsR10.60biosample.attribute:lat_lon42.36 N 71.05 W
SAMN09243345longitude-71.0500R10.90biosample.attribute:lat_lon42.36 N 71.05 W
Sequencing

87 runs over 87 samples · mean 0.70 Gbp per run (median 0.36 Gbp, total 60.87 Gbp; 87 runs with a base count) · layout PAIRED 87 · platform ILLUMINA 87 · models Illumina HiSeq 2500 (87) · 10% of runs with a Sandpiper profile · first public 2019-06-20

Authors (36)

Scheiman J first · Luber JM · Chavkin TA · MacDonald T · Tung A · Pham LD · Wibowo MC · Wurth RC · Punthambaker S · Tierney BT · Yang Z · Hattab MW · Avila-Pacheco J · Clish CB · Lessard S · Church GM · Kostic AD last · Tarracchini C first · Fontana F · Lugli GA · Mancabelli L · Alessandri G · Turroni F · Ventura M · Milani C last · Longhi G · Ormaasen I first · Rudi K · Diep DB · Snipen L last · Wosinska L first · Walsh LH · Walsh CJ · Cotter PD · Guinane CM · O'Sullivan O last

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA472785.csv.gz (3.0 KB) · parquet (73.7 KB) — all 87 samples, every field with route and confidence · PRJNA472785_determinations.csv.gz (3.6 KB) — 513 evidence rows

Samples (87 · every field this project has values for · hover a cell for its source)
Loading the sample table…