Non-nutritive sweeteners and gut microbiome in DC adults
11 fecal samples from adults in Washington, D.C., USA, studied for the effects of non-nutritive sweetener (dietary supplement) intervention on gut microbiome composition. machine-written summary
11 samples · 33 runs · US · Adult · 2018 · 0.89 Gbp / sample · cohort Baseline human gut microbiota profile in healthy p
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 110 sample values (age, bmi, collection date, country, latitude, location locality, location region, longitude) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC6738582 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
Non-microbial dietary supplement (vitamins · population healthy_control · Non-nutritive sweeteners consumed, effect on gut microbiome assessed
“non-nutritive sweeteners influence the gut microbiota” — bioproject.description (study level; per-sample arms are in the intervention column below)
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 11 | 100% | ||||
| country | 11 | 100% | 11 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 11 | 100% | 11 | |||
| age_at_collection_days | 11 | 100% | 11 | |||
| bmi | 11 | 100% | 11 | |||
| collection_date | 11 | 100% | 11 | |||
| detailed_location | 11 | 100% | ||||
| latitude | 11 | 100% | 11 | |||
| location_locality | 11 | 100% | 11 | |||
| location_region | 11 | 100% | 11 | |||
| longitude | 11 | 100% | 11 | |||
| sex | 11 | 100% | 11 |
- Baseline human gut microbiota profile in healthy people and standard reporting template. 2019 PMID 31509535 PMC6738582 unsure
Archive description
A study to evaluate the extent to which non-nutritive sweeteners influence the</p><p>gut microbiota, and to evaluate if prolonged consumption of non-nutritive sweetener alters gut microbiome composition, thereby disturbing metabolic pathways involved in the glycemic control, appetite, and energy metabolism and increasing the risk of obesity.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.72. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site study.title · “human gut microbiome”
- life stage sample.attr.host_age · “18.81 (n=11/11)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN09881644 | age_at_collection_days | 6858.8 | R1 | 0.85 | sample.attr.host_age | 18.81 |
| SAMN09881644 | bmi | 22.92 | R1 | 0.90 | sample.attr.host_body_mass_index | 22.92 |
| SAMN09881644 | collection_date | 2016 | R1 | 0.90 | biosample.attribute:collection_date | 2016 |
| SAMN09881644 | country | US | R1 | 0.90 | sample.attr.geo_loc_name | USA: Washington D.C. |
| SAMN09881644 | latitude | 38.9021 | R1 | 0.90 | biosample.attribute:lat_lon | 38.902096 N 77.051046 W |
| SAMN09881644 | location_locality | Washington | R1 | 0.85 | biosample.attribute:geo_loc_name | USA: Washington D.C. |
| SAMN09881644 | location_region | Washington, D.C. | R1 | 0.60 | biosample.attribute:lat_lon | 38.902096 N 77.051046 W |
| SAMN09881644 | longitude | -77.0510 | R1 | 0.90 | biosample.attribute:lat_lon | 38.902096 N 77.051046 W |
| SAMN09881644 | sex | female | R1 | 0.90 | sample.attr.host_sex | female |
| SAMN09881644 | subject_id | 3 | R1 | 0.85 | sample.attr.host_subject_id | 3 |
Sequencing
33 runs over 11 samples · mean 0.31 Gbp per run (median 0.34 Gbp, total 10.09 Gbp; 33 runs with a base count) · layout PAIRED 33 · platform ILLUMINA 33 · models Illumina MiSeq (33) · 0% of runs with a Sandpiper profile · first public 2018-08-24
Authors (40)
King CH first · Desai H · Sylvetsky AC · LoTempio J · Ayanyan S · Carrie J · Crandall KA · Fochtman BC · Gasparyan L · Gulzar N · Howell P · Issa N · Krampis K · Mishra L · Morizono H · Pisegna JR · Rao S · Ren Y · Simonyan V · Smith K · VedBrat S · Yao MD · Mazumder R last · Argentini C first · Lugli GA · Tarracchini C · Fontana F · Mancabelli L · Viappiani A · Anzalone R · Angelini L · Alessandri G · Longhi G · Bianchi MG · Taurino G · Bussolati O · Milani C · van Sinderen D · Turroni F · Ventura M last
Downloads
PRJNA487305.csv.gz (1.3 KB) · parquet (70.9 KB) — all 11 samples, every field with route and confidence · PRJNA487305_determinations.csv.gz (1.6 KB) — 110 evidence rows