Fecal transplant effects in healthy adults, Saint Petersburg
17 fecal metagenome samples from healthy adult volunteers in Saint Petersburg, Russia, studying gut microbiota changes after capsule fecal microbiota transplantation (FMT) in an intervention design. machine-written summary
17 samples · 17 runs · RU · Adult · 2018 · 5.14 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 119 sample values (collection date, country, latitude, location locality, location region, longitude, timepoint) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 34 sample values (health condition, health condition detail) · PMC12180181, PMC6938016, PMC8407411 |
| ✓ Supplementary tables | 17 sample values (subject id) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Faecal microbiota transplantation design single_arm_before_after · population healthy_control · Capsule fecal microbiota transplantation in healthy volunteers, before/after
“three healthy volunteers before and after capsule FMT” — abstract:31888470 (study level; per-sample arms are in the intervention column below)
longitudinalFMT donor → recipient — not resolved
4 of 4 people sampled more than once (17 samples; median 4, up to 6 per person) · follow-up median 10 mo (max 10 mo) · median interval between samples 24 d (time from collection dates). Schedule stated by the source: “ten time points for V1 (incl. before/after 2nd FMT at day 38); follow-up 300-303 days” (time origin: transplant); stated follow-up 10 mo.
Each row is one person (4 shown); dots are samples at days since that person's first sample.
Capsule FMT from one donor to 3 healthy volunteers; donor vs recipient samples not identified in metadata.
Genera, mean relative abundance over 16 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 17 | 100% | ||||
| country | 17 | 100% | 17 | |||
| health_condition | 17 | 100% | 17 | |||
| subject_id | 17 | 100% | 17 | |||
| collection_date | 17 | 100% | 17 | |||
| detailed_location | 17 | 100% | ||||
| health_condition_detail | 17 | 100% | 17 | |||
| latitude | 17 | 100% | 17 | |||
| location_locality | 17 | 100% | 17 | |||
| location_region | 17 | 100% | 17 | |||
| longitude | 17 | 100% | 17 | |||
| timepoint_label | 17 | 100% | 17 |
- Long-term impact of fecal transplantation in healthy volunteers. 2019 PMID 31888470 PMC6938016 own_data
- Separation of Donor and Recipient Microbial Diversity Allows Determination of Taxonomic and Functional Features of Gut Microbiota Restructuring following Fecal Transplantation. 2021 PMID 34402648 PMC8407411 unsure
- Engrafting gut bacteriophages have potential to modulate microbial metabolism in fecal microbiota transplantation. 2025 PMID 40542451 PMC12180181 unsure
Archive description
WGS metagenomics sequencing data describing fecal transplant influence on healthy voluntaries.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_unknown_no_evidence”
- body site study.title · “Fecal transplant influence on”
- body site study.description · “sequencing data describing fecal transplant influence on”
- life stage study.title · “influence on healthy volunteers”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN10593401 | collection_date | 2017-02-17 | R1 | 0.90 | biosample.attribute:collection_date | 2017-02-17 |
| SAMN10593401 | country | RU | R1 | 0.90 | sample.attr.geo_loc_name | Russia:Saint-Petersburg |
| SAMN10593401 | health_condition | healthy_control | R3 | 0.70 | paper.fulltext.abstract | effects of FMT on the gut microbiota composition in healthy volunteers |
| SAMN10593401 | health_condition_detail | healthy volunteers | R3 | 0.70 | paper.fulltext.abstract | effects of FMT on the gut microbiota composition in healthy volunteers |
| SAMN10593401 | latitude | 59.5600 | R1 | 0.90 | biosample.attribute:lat_lon | 59.56 N 30.20 E |
| SAMN10593401 | location_locality | Saint Petersburg | R1 | 0.75 | biosample.attribute:geo_loc_name | Russia:Saint-Petersburg |
| SAMN10593401 | location_region | Saint Petersburg | R1 | 0.75 | biosample.attribute:geo_loc_name | Russia:Saint-Petersburg |
| SAMN10593401 | longitude | 30.2000 | R1 | 0.90 | biosample.attribute:lat_lon | 59.56 N 30.20 E |
| SAMN10593401 | subject_id | V1 | R2 | 0.80 | paper.supp.12866_2019_1689_MOESM6_ESM.xlsx[Table S1!Subject_ID] | 21 V1 0 |
| SAMN10593401 | timepoint_label | T21 | R1 | 0.70 | sample.name_rule:run_alias | SPB_T21_L1S1_S34_R1_001.fastq.gz |
Sequencing
17 runs over 17 samples · mean 5.10 Gbp per run (median 5.14 Gbp, total 86.74 Gbp; 17 runs with a base count) · layout PAIRED 17 · platform ILLUMINA 17 · models Illumina HiSeq 2500 (17) · 94% of runs with a Sandpiper profile · first public 2018-12-15
Authors (34)
Goloshchapov OV first · Olekhnovich EI · Sidorenko SV · Moiseev IS · Kucher MA · Fedorov DE · Pavlenko AV · Manolov AI · Gostev VV · Veselovsky VA · Klimina KM · Kostryukova ES · Bakin EA · Shvetcov AN · Gumbatova ED · Klementeva RV · Shcherbakov AA · Gorchakova MV · Egozcue JJ · Pawlowsky-Glahn V · Suvorova MA · Chukhlovin AB · Govorun VM · Ilina EN · Afanasyev BV last · Ivanov AB · Ulyantsev VI · Ji S first · Ahmad F · Peng B · Yang Y · Su M · Zhao X · Vatanen T last
Downloads
PRJNA510036.csv.gz (1.4 KB) · parquet (71.2 KB) — all 17 samples, every field with route and confidence · PRJNA510036_determinations.csv.gz (2.4 KB) — 170 evidence rows