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PRJNA517801 SRP182954

Gut metagenomes in liver disease vs healthy controls, Japan

WGS_Liver_disease

Case-control study of 68 fecal WGS samples from liver disease patients and healthy controls in Kanazawa, Japan, examining gut microbiota composition. machine-written summary

68 samples · 68 runs · JP · Age unknown · 2019 · 0.52 Gbp / sample

Sources
✓Sequence archive 498✓Abstract / description 23○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive498 sample values (collection date, country, health condition, health condition detail, latitude, location locality, longitude, subject id)
✓ Abstract / description23 sample values (health condition detail)
○ Full textread; no usable statement or table · PMC12390848
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown68
Condition
healthy_control24
liver_disease21
Country
JP68
Body site
primary68
Collected 2013–2020
2013: 15 samples2014: 21 samples2015: 8 samples2020: 24 samples20132020
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 3 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 65 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.52 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country68 100%68
health_condition45 66%45
subject_id68 100%68
collection_date68 100%68
detailed_location68 100%
health_condition_detail68 100%4523
latitude68 100%68
location_locality68 100%68
longitude68 100%68
Papers (1)
Details
Archive description

WGS of fecal DNA obtained from liver disease patients and healthy controls

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.description · “fecal DNA obtained from liver disease patients”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN10845506collection_date2013-08-30R10.90biosample.attribute:collection_date2013-08-30
SAMN10845506countryJPR10.90sample.attr.geo_loc_nameJapan: Kanazawa
SAMN10845506health_conditionhealthy_controlR10.70sample.name_rule:library_namesHD1
SAMN10845506health_condition_detailHDR10.70sample.name_rule:library_namesHD1
SAMN10845535health_condition_detailmixed_case_control: Cohort includes both liver disease patients and healthy controls; no single condition applies to allR40.50study.descriptionliver disease patients and healthy controls
SAMN10845506latitude36.5500R10.90biosample.attribute:lat_lon36.55 N 136.67 E
SAMN10845506location_localityKanazawaR10.85biosample.attribute:geo_loc_nameJapan: Kanazawa
SAMN10845506longitude136.6700R10.90biosample.attribute:lat_lon36.55 N 136.67 E
SAMN10845506subject_idHD1R10.85biosample.attribute:library_nameslibrary_names: HD1
Sequencing

68 runs over 68 samples · mean 0.53 Gbp per run (median 0.52 Gbp, total 36.10 Gbp; 68 runs with a base count) · layout PAIRED 68 · platform ILLUMINA 68 · models Illumina MiSeq (68) · 0% of runs with a Sandpiper profile · first public 2019-02-01 – 2021-03-13

Authors (43)

Tarracchini C first · Lugli GA · Mancabelli L · van Sinderen D · Turroni F · Ventura M · Milani C last · Lin NY first · Fukuoka S · Koyama S · Motooka D · Tourlousse DM · Shigeno Y · Matsumoto Y · Yamano H · Murotomi K · Tamaki H · Irie T · Sugiyama E · Kumagai S · Itahashi K · Tanegashima T · Fujimaki K · Ito S · Shindo M · Tsuji T · Wake H · Watanabe K · Maeda Y · Enokida T · Tahara M · Yamashita R · Fujisawa T · Nomura M · Kawazoe A · Goto K · Doi T · Shitara K · Mano H · Sekiguchi Y · Nakamura S · Benno Y · Nishikawa H last

Downloads

PRJNA517801.csv.gz (2.9 KB) · parquet (73.6 KB) — all 68 samples, every field with route and confidence · PRJNA517801_determinations.csv.gz (5.0 KB) — 521 evidence rows

Samples (68 · every field this project has values for · hover a cell for its source)
Loading the sample table…