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PRJNA527208 SRP188507

Gut microbiome of Yanomami hunter-gatherers, Brazil

Gut microbiome of the Yanomami from Brazil

Cross-sectional shotgun metagenome study of 15 gut microbiome samples from Yanomami individuals in the Amazon Forest, Brazil, all healthy controls, examined in relation to sunlight exposure and gut microbiome composition. machine-written summary

15 samples · 15 runs · BR · Age unknown · 2019 · 1.84 Gbp / sample · cohort A plasmid network from the gut microbiome of semi-

Sources
✓Sequence archive 90○Abstract / description✓Full text 30○Supplementary tables✓External resources 45–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive90 sample values (collection date, country, latitude, location site, longitude, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text30 sample values (lifestyle, lifestyle detail) · PMC10641926, PMC6682603, PMC7524261, PMC9287393
○ Supplementary tablesfiles read; no table could be matched to the samples
✓ External resources45 sample values (antibiotic exposure, health condition, health condition detail) · from curatedMetagenomicData 3 (cMD 3)
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown15
Condition
healthy_control15
Country
BR15
Body site
primary15
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 1 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 2 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 2 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 9 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.84 Gbp per sample0130Gbp
Community composition
CAG-196 7.3%UBA2883 5.4%Stercorousia 4.8%CAIQDX01 3.4%Treponema_D 3.1%Prevotella 3.0%Succinivibrio 2.7%UMGS1585 2.2%QHMH01 1.8%Campylobacter 1.4%UBA6448 1.4%Zag111 1.3%not assigned to a genus 41.5%other genera 20.6%

Genera, mean relative abundance over 11 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country15 100%15
health_condition15 100%15
subject_id15 100%15
antibiotic_exposure15 100%15
collection_date15 100%15
detailed_location15 100%
health_condition_detail15 100%15
latitude15 100%15
lifestyle15 100%15
lifestyle_detail15 100%15
location_site15 100%15
longitude15 100%15
Papers (10)
  • Skin exposure to sunlight: a factor modulating the human gut microbiome composition. 2020 PMID 32339065 PMC7524261 own_data
  • Gut Microbiome Biomarkers and Functional Diversity Within an Amazonian Semi-Nomadic Hunter-Gatherer Group. 2019 PMID 31417531 PMC6682603 own_data
  • A plasmid network from the gut microbiome of semi-isolated human groups reveals unique and shared metabolic and virulence traits. 2022 PMID 35840779 PMC9287393 own_data
  • Heavy metal resistance in the Yanomami and Tunapuco microbiome. 2023 PMID 37971084 PMC10641926 own_data
  • Meta-analysis of the uncultured gut microbiome across 11,115 global metagenomes reveals a new candidate biomarker of health 2025 own_data
5 more
  • Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides. 2020 PMID 32265336 PMC7157763
  • Human Gut Faecalibacterium prausnitzii Deploys a Highly Efficient Conserved System To Cross-Feed on β-Mannan-Derived Oligosaccharides. 2021 PMID 34061597 PMC8262883
  • Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria. 2022 PMID 35240043 PMC9096808
  • The gut microbiome of Baka forager-horticulturalists from Cameroon is optimized for wild plant foods. 2024 PMID 38433907 PMC10904984
  • The molecular basis of cereal mixed-linkage β-glucan utilization by the human gut bacterium Segatella copri. 2024 PMID 39122003 PMC11418011
Details
Archive description

Shotgun metagenome sequencing of the gut microbiome of the Yanomami from Brazil

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host study.title · “Gut microbiome of the Yanomami from Brazil”
  • body site study.description · “gut microbiome of the Yanomami from Brazil”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN11130569antibiotic_exposurenoR20.75external.cmd sourceantibiotics_current_use: No
SAMN11130569collection_date2015R10.90biosample.attribute:collection_date2015
SAMN11130569countryBRR10.90sample.attr.geo_loc_nameBrazil:Amazon Forest
SAMN11130569health_conditionhealthy_controlR20.75external.cmd sourcedisease: Healthy
SAMN11130569health_condition_detailHealthyR20.75external.cmd sourcedisease: Healthy
SAMN11130569latitude1.1958R10.90biosample.attribute:lat_lon1.195811 N 64.8105 W
SAMN11130569lifestylehunter_gathererR30.70paper.fulltext.methodssemi-isolated hunter-gatherer community from the Brazilian Amazon
SAMN11130569lifestyle_detailYanomamiR30.70paper.fulltext.methodsthe Yanomami (n = 15)
SAMN11130569location_siteAmazon ForestR10.85biosample.attribute:geo_loc_nameBrazil:Amazon Forest
SAMN11130569longitude-64.8105R10.90biosample.attribute:lat_lon1.195811 N 64.8105 W
SAMN11130569subject_idAH08R10.85sample.attr.host_subject_idAH08
Sequencing

15 runs over 15 samples · mean 1.57 Gbp per run (median 1.84 Gbp, total 23.56 Gbp; 15 runs with a base count) · layout SINGLE 15 · platform ILLUMINA 15 · models Illumina HiSeq 2500 (15) · 73% of runs with a Sandpiper profile · first public 2019-10-12

Authors (26)

Conteville LC first · Oliveira-Ferreira J · Vicente ACP last · Tarracchini C first · Fontana F · Mancabelli L · Lugli GA · Alessandri G · Turroni F · Ventura M · Milani C last · De Biase R · Bocchio F · Viappiani A · De Conto F · Nouvenne A · Ticinesi A · Bussolati O · Meschi T · Cecchi R · van Sinderen D · da Silva AC first · Lapkin J · Yin Q · Muller E · Almeida A last

Downloads

PRJNA527208.csv.gz (1.3 KB) · parquet (70.9 KB) — all 15 samples, every field with route and confidence · PRJNA527208_determinations.csv.gz (2.2 KB) — 165 evidence rows

Samples (15 · every field this project has values for · hover a cell for its source)
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