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PRJNA542578 SRP202040

Gut microbiota and longevity in Guangxi, China

human gut metagenome Raw sequence reads

Cross-sectional study of 151 samples from healthy individuals in Yongfu County, Guangxi, China, spanning middle-aged, elderly, nonagenarian, and centenarian age groups, examining the relationship between gut microbiota and longevity. machine-written summary

151 samples · 151 runs · CN · Elderly · 2024 · 13.05 Gbp / sample · cohort Age-dependent changes in the gut microbiota and se

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Sources
✓Sequence archive 906○Abstract / description✓Full text 302✓Supplementary tables 299✓External resources 302–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive906 sample values (collection date, country, latitude, location region, longitude, subject id)
○ Abstract / descriptionread; no usable statement
✓ Full text302 sample values (antibiotic exposure, location locality) · PMC10726799
✓ Supplementary tables299 sample values (age, bmi)
✓ External resources302 sample values (health condition, health condition detail) · from GMrepo v3
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
2 sampling locations · 1 country
Age
elderly100
adult51
Condition
healthy_control151
Country
CN151
Body site
primary151
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 1 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 30 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 120 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 13.05 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category151 100%
country151 100%151
health_condition151 100%151
subject_id151 100%151
age_at_collection_days151 100%151
antibiotic_exposure151 100%151
collection_date151 100%151
detailed_location151 100%
health_condition_detail151 100%151
latitude151 100%151
location_locality151 100%151
location_region151 100%151
longitude151 100%151
bmi148 98%148
Papers (1)
  • Age-dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging. 2023 PMID 38015106 PMC10726799 own_data
Details
Archive description

In order to study the relationship between gut microbiota and longevity, we collected included 151 healthy people (50.33% female) at Yongfu County, Guangxi, China: 29 individuals aged 100-111 (Centenarians) and 46 individuals aged 90-100(Nonagenarians) and 40 individuals aged 60-90(Elderly) and 36 individuals aged 20-60(Middle-aged)

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult and elderly by opus_adjudicated with confidence 0.80. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • host study.description · “151 healthy people (50.33% female)”
  • body site study.description · “relationship between gut microbiota and longevity”
  • life stage study.description · “29 individuals aged 100-111 (Centenarians)”
  • life stage study.description · “36 individuals aged 20-60(Middle-aged)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN11960282age_at_collection_days34334.0R20.85paper.supp.ACEL-22-e14028-s002.xlsx[Supplementary Table 1!Age]S5073 | 94
SAMN11960282antibiotic_exposurenoR30.70paper.body.methods_resultsThe exclusion criteria included self‐reported antibiotic use within 1 month
SAMN11960282bmi17.47R20.85paper.supp.ACEL-22-e14028-s002.xlsx[Supplementary Table 1!BMI]S5073 | 17.47191251
SAMN11960282collection_date2017-01-06R10.90biosample.attribute:collection_date2017-01-06
SAMN11960282countryCNR10.90sample.attr.geo_loc_nameChina:Guangxi
SAMN11960282health_conditionhealthy_controlR20.75external.gmrepo sourcephenotype: Health
SAMN11960282health_condition_detailHealthR20.75external.gmrepo sourcephenotype: Health
SAMN11960282latitude24.9800R10.90biosample.attribute:lat_lon24.98 N 109.98 E
SAMN11960282location_localityYongfu CountyR30.70paper.body.methods_resultswe recruited 151 healthy individuals from Yongfu County
SAMN11960282location_regionGuangxiR10.85biosample.attribute:geo_loc_nameChina:Guangxi
SAMN11960282longitude109.9800R10.90biosample.attribute:lat_lon24.98 N 109.98 E
SAMN11960282subject_idS5073R10.85biosample.attribute:aliasalias: S5073
Sequencing

151 runs over 151 samples · mean 13.66 Gbp per run (median 13.05 Gbp, total 2,062.00 Gbp; 151 runs with a base count) · layout PAIRED 151 · platform BGISEQ 151 · models BGISEQ-500 (151) · 0% of runs with a Sandpiper profile · first public 2024-04-28

Authors (0)

No author record.

Downloads

PRJNA542578.csv.gz (5.9 KB) · parquet (79.8 KB) — all 151 samples, every field with route and confidence · PRJNA542578_determinations.csv.gz (18.3 KB) — 1,809 evidence rows

Samples (151 · every field this project has values for · hover a cell for its source)
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