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PRJNA554501 SRP214743

Gut microbiome of Chinese navy sailors on long sea voyage

Navy voyage feces metagenome Metagenome

84 fecal samples from adult sailors in Qingdao, China, in a 30-day longitudinal intervention study comparing probiotic and placebo groups during a long sea voyage. machine-written summary

84 samples · 84 runs · CN · Adult · 2020 · 6.80 Gbp / sample

Sources
✓Sequence archive 442○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive442 sample values (collection date, country, latitude, location locality, location region, longitude)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC7524324, PMC8318886, PMC8523657
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Probiotic (live microorganisms; single strain or mixture) design randomized_controlled_trial · population healthy_control · Probiotic vs placebo during 30-day sea voyage in sailors

“a placebo group ( n = 42) and a probiotic group” — abstract:32079472 (study level; per-sample arms are in the intervention column below)

Samples at a glance
2 sampling locations · 1 country
Age
adult84
Country
CN84
Body site
primary84
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 84 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.80 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

Schedule stated by the source: “Samples collected at baseline (d0) and end of 30-day sea voyage (d30) in placebo and probiotic groups.” (time origin: intervention start); stated follow-up 30 d.

How longitudinal and relatedness information is derived

Community composition
Prevotella 14.7%Faecalibacterium 9.5%Phocaeicola 9.1%Roseburia 9.0%Bacteroides 5.8%Fusicatenibacter 3.9%Blautia_A 2.7%Bifidobacterium 2.4%Lachnospira 2.1%Mediterraneibacter 1.8%Dialister 1.7%Alistipes 1.6%not assigned to a genus 3.5%other genera 32.2%

Genera, mean relative abundance over 79 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category84 100%
country84 100%84
health_condition0 0%
subject_id0 0%
collection_date84 100%84
detailed_location84 100%
latitude84 100%84
location_locality84 100%84
longitude84 100%84
location_region22 26%22
Papers (3)
  • Probiotics maintain the intestinal microbiome homeostasis of the sailors during a long sea voyage. 2020 PMID 32079472 PMC7524324 own_data
  • Probiotics impact the antibiotic resistance gene reservoir along the human GI tract in a person-specific and antibiotic-dependent manner. 2021 PMID 34226711 PMC8318886 unsure
  • Probiotic consumption influences universal adaptive mutations in indigenous human and mouse gut microbiota. 2021 PMID 34663913 PMC8523657 unsure
Details
Archive description

Probiotics maintain the intestinal microbiome homeostasis of Chinese navy during a long sea voyage

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.75. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “Navy voyage feces metagenome”
  • life stage study.description · “Chinese navy during a long sea voyage”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN12272181collection_date2017-10-10R10.90biosample.attribute:collection_date2017-10-10
SAMN12272181countryCNR10.90sample.attr.geo_loc_nameChina: Qingdao
SAMN12272181latitude36.0600R10.90biosample.attribute:lat_lon36.06 N 120.38 E
SAMN12272181location_localityQingdaoR10.85biosample.attribute:geo_loc_nameChina: Qingdao
SAMN12272181location_regionShandong ShengR10.60biosample.attribute:lat_lon36.06 N 120.38 E
SAMN12272181longitude120.3800R10.90biosample.attribute:lat_lon36.06 N 120.38 E
Sequencing

84 runs over 84 samples · mean 6.80 Gbp per run (median 6.80 Gbp, total 571.22 Gbp; 84 runs with a base count) · layout PAIRED 84 · platform ILLUMINA 84 · models Illumina HiSeq 4000 (84) · 94% of runs with a Sandpiper profile · first public 2020-02-05

Authors (24)

Zhang J first · Zhao J · Jin H · Lv R · Shi H · De G · Yang B · Sun Z · Zhang H last · Montassier E first · Valdés-Mas R · Batard E · Zmora N · Dori-Bachash M · Suez J · Elinav E last · Ma C first · Zhang C · Chen D · Jiang S · Shen S · Huo D · Huang S · Zhai Q

Help complete this project

2 of the 4 core fields are below 50% coverage: health_condition, subject_id. Share metadata

Downloads

PRJNA554501.csv.gz (3.1 KB) · parquet (73.4 KB) — all 84 samples, every field with route and confidence · PRJNA554501_determinations.csv.gz (3.8 KB) — 442 evidence rows

Samples (84 · every field this project has values for · hover a cell for its source)
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