Gut microbiome in ALS patients versus spouse controls
18 samples from a gut microbiome study comparing ALS patients to their spouses, with healthy opposite-sex couples from the same region as additional controls. machine-written summary
18 samples · 18 runs · US · Age unknown · 2019 · 5.5 Mbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 108 sample values (collection date, country, family id, family role, health condition, health condition detail) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC10676149 |
| ✓ Supplementary tables | 18 sample values (subject id) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
partners / couples
9 ALS patient–spouse couples (18 people, one stool each); published subject_id merges spouses · 9 families with 18 sampled people.
partner · circles are people (pale = no sequenced sample), arrows run donor → recipient and parent → child, curved lines join twins, partners and siblings, squares are shared settings or families without recorded roles. Shown: 9 linked groups from explicit relations. 18 people in the project overall.
Families (9)
| family | members | samples |
|---|---|---|
| 1 | partner×2 | SAMN12791223 · SAMN12791224 |
| 10 | partner×2 | SAMN12791239 · SAMN12791240 |
| 2 | partner×2 | SAMN12791225 · SAMN12791226 |
| 3 | partner×2 | SAMN12791227 · SAMN12791228 |
| 5 | partner×2 | SAMN12791229 · SAMN12791230 |
| 6 | partner×2 | SAMN12791231 · SAMN12791232 |
| 7 | partner×2 | SAMN12791233 · SAMN12791234 |
| 8 | partner×2 | SAMN12791235 · SAMN12791236 |
| 9 | partner×2 | SAMN12791237 · SAMN12791238 |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 18 | 100% | ||||
| country | 18 | 100% | 18 | |||
| health_condition | 18 | 100% | 18 | |||
| subject_id | 18 | 100% | 18 | |||
| collection_date | 18 | 100% | 18 | |||
| family_id | 18 | 100% | 18 | |||
| family_role | 18 | 100% | 18 | |||
| health_condition_detail | 18 | 100% | 18 |
- Gut microbiome differences between amyotrophic lateral sclerosis patients and spouse controls. 2022 PMID 33818222 PMC10676149 cites_accession
Archive description
Gut microbiome differs between ALS patients and spouse controls
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.70. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host study.description · “ALS patients and spouse controls”
- body site study.description · “Gut microbiome differs between ALS patients”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN12791223 | collection_date | 2016-06-24 | R1 | 0.85 | biosample.attribute:collection_date | collection_date: 2016-06-24 |
| SAMN12791223 | country | US | R1 | 0.85 | biosample.attribute:geo_loc_name | geo_loc_name: USA:Atlanta, GA |
| SAMN12791223 | family_id | 1 | R1 | 0.85 | biosample.attribute:pair | pair: 1 |
| SAMN12791223 | family_role | partner | R1 | 0.85 | biosample.attribute:pair+status | pair: 1; status: ALS |
| SAMN12791223 | health_condition | neurological_psychiatric | R1 | 0.85 | biosample.attribute:Status | Status: ALS |
| SAMN12791223 | health_condition_detail | ALS | R1 | 0.85 | biosample.attribute:Status | Status: ALS |
| SAMN12791223 | subject_id | 1_ALS | R2 | 0.80 | archive |
Sequencing
18 runs over 18 samples · mean 5.5 Mbp per run (median 5.5 Mbp, total 98.7 Mbp; 18 runs with a base count) · layout PAIRED 18 · platform ILLUMINA 18 · models Illumina MiSeq (18) · 0% of runs with a Sandpiper profile · first public 2019-09-22
Authors (0)
No author record.
Downloads
PRJNA566436.csv.gz (1.4 KB) · parquet (70.2 KB) — all 18 samples, every field with route and confidence · PRJNA566436_determinations.csv.gz (2.0 KB) — 126 evidence rows