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PRJNA588627 SRP230281

Gut phageome in type 2 diabetes, Shanghai, China

human gut metagenome Metagenome

A gut metagenome sample from Shanghai, China, studied for enteric phageome alterations associated with type 2 diabetes; design listed as "other." machine-written summary

46 samples · 46 runs · CN · Age unknown · 2019 · 11.23 Gbp / sample

Sources
✓Sequence archive 92○Abstract / description✓Full text 138✓Supplementary tables 34–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive92 sample values (health condition, health condition detail)
○ Abstract / descriptionread; no usable statement
✓ Full text138 sample values (antibiotic exposure, country, location region) · PMC7862107
✓ Supplementary tables34 sample values (bmi, medication)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown46
Condition
healthy_control29
type2_diabetes17
Country
CN46
Body site
primary46
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 9 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 37 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 11.23 Gbp per sample0130Gbp
Community composition
Alistipes 6.4%CAG-302 5.9%Bacteroides 5.8%CAG-452 4.8%Phocaeicola 4.1%Bradyrhizobium 3.8%CAG-245 3.7%CAG-417 3.1%Bifidobacterium 2.9%DNVW01 2.6%CAG-273 2.2%Faecalibacterium 1.9%not assigned to a genus 10.7%other genera 42.0%

Genera, mean relative abundance over 1 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country46 100%46
health_condition46 100%46
subject_id0 0%
antibiotic_exposure46 100%46
detailed_location46 100%
health_condition_detail46 100%46
location_region46 100%46
bmi17 37%17
medication17 37%17
Papers (1)
Details
Archive description

Enteric phageome alternations in Type 2 diabetes disease

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.78. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “human gut metagenome Metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SRR10479802antibiotic_exposurenoR30.70paper.body.methodsThose who received antibiotics in the preceding 3 months were excluded from this study.
SRR10479802bmi27.58R20.80paper.supp.DataSheet_1.docx[Supplementary Table 6!height (cm);Weight (kg)]subject D10: height 166 cm, weight 76 kg
SRR10479802countryCNR30.70paper.body.methodsPatients with T2D involved in this study were recruited from Shanghai Jiao Tong University Affiliated Sixth People’s Hospital.
SRR10479802health_conditiontype2_diabetesR10.70sample.name_rule:library_namelibrary_name: D10
SRR10479802health_condition_detailT2DR10.70sample.name_rule:library_namelibrary_name: D10
SRR10479802location_regionShanghaiR30.70paper.body.methodsHealthy volunteers aged 20 to 50 years old in the control group were recruited from Shanghai Jiao Tong University Affiliated Sixth People’s Hospital.
SRR10479802medicationantidiabetic_other;metformin;statinR20.85paper.supp.DataSheet_1.docx[Supplementary Tables 7-8!drug columns =1]subject D10: Insulin, Metformin, Statin, TZD = 1
Sequencing

46 runs over 46 samples · mean 11.72 Gbp per run (median 11.23 Gbp, total 539.07 Gbp; 46 runs with a base count) · layout PAIRED 46 · platform ILLUMINA 46 · models HiSeq X Ten (46) · 91% of runs with a Sandpiper profile · first public 2019-11-19

Authors (0)

No author record.

Downloads

PRJNA588627.csv.gz (2.0 KB) · parquet (70.9 KB) — all 46 samples, every field with route and confidence · PRJNA588627_determinations.csv.gz (3.7 KB) — 264 evidence rows

Samples (46 · every field this project has values for · hover a cell for its source)
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