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PRJNA596624 SRP238198

Gut metagenome of healthy Thai adults given prebiotic CMH

Human gut metagenome

10 fecal metagenome samples from healthy adults in Thailand, studying the effect of copra meal hydrolysate (CMH) prebiotic treatment on gut microbiome composition and SCFA-related metabolic routes, using an intervention design. machine-written summary

10 samples · 10 runs · TH · Adult · 2024 · 17.81 Gbp / sample

Sources
✓Sequence archive 60✓Abstract / description 20✓Full text 30○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive60 sample values (collection date, country, latitude, longitude, subject id, timepoint)
✓ Abstract / description20 sample values (health condition, health condition detail)
✓ Full text30 sample values (antibiotic exposure, location locality, location site) · PMC12966491, PMC9855101
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Prebiotic / dietary fibre supplement design single_arm_before_after · population healthy_control · Copra meal hydrolysate (CMH) prebiotic treatment in healthy Thai adults

“healthy adults who received prebiotics diet” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
adult10
Condition
healthy_control10
Country
TH10
Body site
primary10
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 10 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 17.81 Gbp per sample0130Gbp
Community composition
Bifidobacterium 14.3%Faecalibacterium 11.4%Roseburia 6.7%Streptococcus 6.3%Gemmiger 5.8%Escherichia 5.7%Collinsella 4.3%Fimenecus 2.7%Holdemanella 2.2%Klebsiella 2.0%Agathobaculum 1.8%Vescimonas 1.8%not assigned to a genus 3.8%other genera 31.3%

Genera, mean relative abundance over 9 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category10 100%
country10 100%10
health_condition10 100%10
subject_id10 100%10
antibiotic_exposure10 100%10
collection_date10 100%10
detailed_location10 100%
health_condition_detail10 100%10
latitude10 100%10
location_locality10 100%10
location_site10 100%10
longitude10 100%10
timepoint_label10 100%10
Papers (2)
  • Analyzing Predominant Bacterial Species and Potential Short-Chain Fatty Acid-Associated Metabolic Routes in Human Gut Microbiome Using Integrative Metagenomics. 2022 PMID 36671714 PMC9855101 own_data
  • Modeling diet-gut microbiome interactions and prebiotic responses in Thai adults. 2026 PMID 41605932 PMC12966491 unsure
Details
Archive description

Total microbial community DNA was isolated from the fecal samples of healthy adults who received prebiotics diet.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Human gut metagenome”
  • body site study.description · “isolated from the fecal samples of healthy”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • life stage study.description · “samples of healthy adults who received prebiotics”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN13632796antibiotic_exposurenoR30.70paper.fulltext.methodsnot receive antibiotics within at least three months
SAMN13632796collection_date2019R10.90biosample.attribute:collection_date2019
SAMN13632796countryTHR10.90sample.attr.geo_loc_nameThailand
SAMN13632796health_conditionhealthy_controlR40.50study.descriptionhealthy adults who received prebiotics
SAMN13632796health_condition_detailhealthy adults receiving prebiotic diet interventionR40.50study.descriptionhealthy adults who received prebiotics
SAMN13632796latitude13.4500R10.90biosample.attribute:lat_lon13.45 N 100.31 E
SAMN13632796location_localityBangkokR30.70paper.fulltext.methodsThai adults—from Bangkok and its closer city
SAMN13632796location_siteKing Chulalongkorn Memorial HospitalR30.70paper.fulltext.methodsinformed at King Chulalongkorn Memorial Hospital, Bangkok, Thailand
SAMN13632796longitude100.3100R10.90biosample.attribute:lat_lon13.45 N 100.31 E
SAMN13632796subject_id461KR10.70sample.name_rule:aliasA_461K_BV3D21
SAMN13632796timepoint_labelV3D21R10.70sample.name_rule:aliasA_461K_BV3D21
Sequencing

10 runs over 10 samples · mean 17.75 Gbp per run (median 17.81 Gbp, total 177.53 Gbp; 10 runs with a base count) · layout PAIRED 10 · platform ILLUMINA 10 · models HiSeq X Ten (10) · 90% of runs with a Sandpiper profile · first public 2024-06-04

Authors (8)

Kingkaw A first · Raethong N · Patumcharoenpol P · Suratannon N · Nakphaichit M · Keawsompong S · Roytrakul S · Vongsangnak W last

Downloads

PRJNA596624.csv.gz (1.3 KB) · parquet (71.2 KB) — all 10 samples, every field with route and confidence · PRJNA596624_determinations.csv.gz (1.7 KB) — 110 evidence rows

Samples (10 · every field this project has values for · hover a cell for its source)
Loading the sample table…