Gut microbiome in longevous Chinese cohort, Jiangsu
Cross-sectional study of 348 gut metagenome samples from a longevous Chinese cohort (elderly and adult) in Jiangsu, China, including healthy controls and individuals with cardiometabolic conditions or type 2 diabetes. machine-written summary
348 samples · 348 runs · CN · Adult · 2020 · 6.33 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 1,740 sample values (collection date, country, latitude, location region, longitude) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC10609127, PMC11364081, PMC11559365, PMC12810900, PMC9892008 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| ✓ External resources | 2,028 sample values (age, antibiotic exposure, bmi, health condition, health condition detail, sex) · from curatedMetagenomicData 3 (cMD 3) |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
parent–child — not resolved
Longevous Chinese cohort (elderly, 50–105y, incl. centenarians) plus their biological offspring (50–79y); 116 elderly + 232 offspring = 348 samples total..
Genera, mean relative abundance over 321 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 332 | 95% | ||||
| country | 348 | 100% | 348 | |||
| health_condition | 327 | 94% | 327 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 348 | 100% | 348 | |||
| detailed_location | 348 | 100% | ||||
| latitude | 348 | 100% | 348 | |||
| location_region | 348 | 100% | 348 | |||
| longitude | 348 | 100% | 348 | |||
| sex | 347 | 100% | 347 | |||
| age_at_collection_days | 343 | 99% | 343 | |||
| bmi | 343 | 99% | 343 | |||
| antibiotic_exposure | 341 | 98% | 341 | |||
| health_condition_detail | 327 | 94% | 327 |
- The person-to-person transmission landscape of the gut and oral microbiomes. 2023 PMID 36653448 PMC9892008 own_data
- Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study. 2026 PMID 41525322 PMC12810900 own_data
- A Pipeline for Constructing Reference Genomes for Large Cohort-Specific Metagenome Compression. 2023 PMID 37894218 PMC10609127 unsure
- Consistent signatures in the human gut microbiome of longevous populations. 2024 PMID 39197040 PMC11364081 unsure
- Biosynthetic potential of the gut microbiome in longevous populations. 2024 PMID 39529240 PMC11559365 unsure
Archive description
a study of the signatures of gut microbiota in Chinese cohort of longevous people and their children
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and child by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “human gut metagenome Metagenome”
- body site study.description · “the signatures of gut microbiota in Chinese”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- life stage study.description · “people and their children”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN14445420 | age_at_collection_days | 23376.0 | R2 | 0.75 | external.cmd source | age: 64; age_unit: (empty); age_group: Adult |
| SAMN14445420 | antibiotic_exposure | no | R2 | 0.75 | external.cmd source | antibiotics_current_use: No |
| SAMN14445420 | bmi | 27.06 | R2 | 0.75 | external.cmd source | bmi: 27.05515088 |
| SAMN14445420 | collection_date | 2016 | R1 | 0.90 | biosample.attribute:collection_date | 2016 |
| SAMN14445420 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Jiangsu |
| SAMN14445421 | health_condition | healthy_control | R2 | 0.75 | external.cmd source | disease: Healthy |
| SAMN14445421 | health_condition_detail | Healthy | R2 | 0.75 | external.cmd source | disease: Healthy |
| SAMN14445420 | latitude | 31.8000 | R1 | 0.90 | biosample.attribute:lat_lon | 31.80 N 121.66 E |
| SAMN14445420 | location_region | Jiangsu | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Jiangsu |
| SAMN14445420 | longitude | 121.6600 | R1 | 0.90 | biosample.attribute:lat_lon | 31.80 N 121.66 E |
| SAMN14445420 | sex | male | R2 | 0.75 | external.cmd source | sex: Male |
Sequencing
348 runs over 348 samples · mean 6.37 Gbp per run (median 6.33 Gbp, total 2,217.52 Gbp; 348 runs with a base count) · layout PAIRED 348 · platform ILLUMINA 348 · models Illumina HiSeq 4000 (348) · 92% of runs with a Sandpiper profile · first public 2020-03-26
Authors (71)
Valles-Colomer M first · Blanco-Míguez A · Manghi P · Asnicar F · Dubois L · Golzato D · Armanini F · Cumbo F · Huang KD · Manara S · Masetti G · Pinto F · Piperni E · Punčochář M · Ricci L · Zolfo M · Farrant O · Goncalves A · Selma-Royo M · Binetti AG · Becerra JE · Han B · Lusingu J · Amuasi J · Amoroso L · Visconti A · Steves CM · Falchi M · Filosi M · Tett A · Last A · Xu Q · Qin N · Qin H · May J · Eibach D · Corrias MV · Ponzoni M · Pasolli E · Spector TD · Domenici E · Collado MC · Segata N last · Wang L first · Ding R · He S · Wang Q · Zhou Y last · Chen S first · Zhang Z · Liu S · Chen T · Lu Z · Zhao W · Mou X · Wang X · Ma Y · Ruan H · Wu X · Li B · Karagiannis TT first · Chen Y · Bald S · Tai A · Reed ER · Milman S · Andersen SL · Perls TT · Segrè D · Sebastiani P · Short MI last
Downloads
PRJNA613947.csv.gz (11.4 KB) · parquet (86.1 KB) — all 348 samples, every field with route and confidence · PRJNA613947_determinations.csv.gz (39.4 KB) — 3,768 evidence rows