Gut microbiota in Chengdu, China long-living cohort
Cross-sectional study of 95 stool samples from Chengdu, China, comparing gut microbiota composition and function across unhealthy long-living, healthy long-living, healthy elderly, and healthy young participant groups. machine-written summary
95 samples · 95 runs · CN · Adult · 2020 · 11.69 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 758 sample values (age, country, health condition, health condition detail, latitude, location locality, longitude, sex) |
| ✓ Abstract / description | 95 sample values (subject id) |
| ○ Full text | read; no usable statement or table · PMC11364081, PMC11488730, PMC13021664, PMC13079874 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
age: two sequence archives disagree for 2 samples (e.g. 102.0 vs 37255.5) — withheld.
The sources disagree on 2 samples. Where two incompatible values exist for one sample (or one person's samples disagree on sex), neither value is published: the field is left empty here, in the sample sheet and in the downloads. Both sides, with their sources, are in gut_metadata_contradictions.parquet of the data package (what counts as a contradiction).
Contradicted values (2)
| sample | field | value | other value | handling |
|---|---|---|---|---|
| SAMN14582934 | age | 102.0 (sequence archive) | 37255.5 (sequence archive) | withheld: neither value published |
| SAMN14582935 | age | 102.0 (sequence archive) | 37255.5 (sequence archive) | withheld: neither value published |
Genera, mean relative abundance over 89 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 95 | 100% | ||||
| country | 95 | 100% | 95 | |||
| health_condition | 95 | 100% | 95 | |||
| subject_id | 95 | 100% | 95 | |||
| detailed_location | 95 | 100% | ||||
| health_condition_detail | 95 | 100% | 95 | |||
| latitude | 95 | 100% | 95 | |||
| location_locality | 95 | 100% | 95 | |||
| longitude | 95 | 100% | 95 | |||
| sex | 95 | 100% | 95 | |||
| age_at_collection_days | 93 | 98% | 93 |
- Consistent signatures in the human gut microbiome of longevous populations. 2024 PMID 39197040 PMC11364081 unsure
- Comprehensive gut microbiota composition and microbial interactions among the three age groups. 2024 PMID 39423213 PMC11488730 unsure
- Examination of shared gut microbiome signatures in aging and Parkinson's disease. 2026 PMID 41907847 PMC13021664 unsure
- Comprehensive benchmarking of metagenomic binning tools reveals key factors for improved genome recovery. 2026 PMID 41980943 PMC13079874 unsure
Archive description
The human gut microbiota in long-living people has been characterized, however, its metabolic potential is still largely unknown in this group. In this study, the gut microbiota was assessed in 95 Chinese participants by metagenomic sequencing of stool samples. Participants were categorized into four groups, unhealthy long-living (n=9), healthy long-living (n=28), healthy elderly (n=31) and healthy young (n=27). Gut microbiota composition and function were compared among these four groups.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and elderly by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “metagenomics of human gut microbiota in China”
- body site study.description · “The human gut microbiota in long-living”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- life stage study.description · “long-living (n=28), healthy elderly (n=31) and healthy”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN14582933 | age_at_collection_days | 37620.8 | R1 | 0.70 | sample.attr.host_age | 103 |
| SAMN14582933 | country | CN | R1 | 0.90 | sample.attr.geo_loc_name | China: Chengdu |
| SAMN14582933 | health_condition | healthy_control | R1 | 0.90 | biosample_attr | Health |
| SAMN14582933 | health_condition_detail | Health | R1 | 0.90 | sample.attr.host_disease | Health |
| SAMN14582933 | latitude | 30.8700 | R1 | 0.90 | biosample.attribute:lat_lon | 30.87 N 103.59 E |
| SAMN14582933 | location_locality | Chengdu | R1 | 0.85 | biosample.attribute:geo_loc_name | China: Chengdu |
| SAMN14582933 | longitude | 103.5900 | R1 | 0.90 | biosample.attribute:lat_lon | 30.87 N 103.59 E |
| SAMN14582933 | sex | female | R1 | 0.90 | sample.attr.host_sex | female |
| SAMN14582933 | subject_id | SAMN14582933 | R4 | 0.60 | design.one_sample_per_subject:description | the gut microbiota was assessed in 95 Chinese participants by metagenomic sequencing of stool samples |
Sequencing
95 runs over 95 samples · mean 11.69 Gbp per run (median 11.69 Gbp, total 1,110.83 Gbp; 95 runs with a base count) · layout PAIRED 95 · platform ILLUMINA 95 · models Illumina NovaSeq 6000 (95) · 94% of runs with a Sandpiper profile · first public 2020-07-22
Authors (39)
Tarracchini C first · Fontana F · Mancabelli L · Lugli GA · Alessandri G · Turroni F · Ventura M · Milani C last · De Biase R · Bocchio F · Viappiani A · De Conto F · Nouvenne A · Ticinesi A · Bussolati O · Meschi T · Cecchi R · Chen S first · Zhang Z · Liu S · Chen T · Lu Z · Zhao W · Mou X · van Sinderen D · Ma J first · Yang X · He J last · Tng TJW first · Vanan S · Tan EK · Zeng L · Goh WWB · Wong SH · Lim KL last · Kim J first · Kim N · Cha JH · Lee I last
Downloads
PRJNA624763.csv.gz (3.8 KB) · parquet (75.4 KB) — all 95 samples, every field with route and confidence · PRJNA624763_determinations.csv.gz (6.2 KB) — 853 evidence rows