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PRJNA647221 SRP273604

FMT Before and After in Ulcerative Colitis, South Korea

Before and after fecal microbiota transplantation in ulcerative colitis patients

1 sample from an adult with ulcerative colitis in South Korea, collected before and after fecal microbiota transplantation as part of an intervention study. machine-written summary

68 samples · 68 runs · Adult · 2024 · 9.15 Gbp / sample

Sources
✓Sequence archive 136✓Abstract / description 136○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive136 sample values (subject id, timepoint)
✓ Abstract / description136 sample values (health condition, health condition detail)
○ Full textread; no usable statement or table · PMC9474483
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Faecal microbiota transplantation design single_arm_before_after · population ulcerative_colitis · Fecal microbiota transplantation in ulcerative colitis patients

“Before and after fecal microbiota transplantation” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
Age
adult68
Condition
ulcerative_colitis68
Body site
primary68
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 42 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 26 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 9.15 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

10 of 10 people sampled more than once (68 samples; median 7, up to 7 per person). Schedule stated by the source: “Fecal samples at T0 (day before FMT), then T1, T7, T28, T35, T58 days after FMT” (time origin: intervention_start); stated follow-up 58 d.

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 22.7%Faecalibacterium 8.1%Prevotella 6.7%Blautia_A 5.0%Phocaeicola 4.2%Collinsella 4.2%Bacteroides 3.8%Fusicatenibacter 2.5%Enterococcus_A 2.1%Megamonas 1.8%Enterococcus_B 1.6%Mediterraneibacter 1.4%not assigned to a genus 4.0%other genera 32.0%

Genera, mean relative abundance over 1 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category68 100%
country0 0%
health_condition68 100%68
subject_id68 100%68
health_condition_detail68 100%68
timepoint_label68 100%68
Papers (1)
  • Exploration of Potential Gut Microbiota-Derived Biomarkers to Predict the Success of Fecal Microbiota Transplantation in Ulcerative Colitis: A Prospective Cohort in Korea. 2022 PMID 35975640 PMC9474483 own_data
Details
Archive description

Before and after fecal microbiota transplantation in ulcerative colitis patients

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Before and after fecal microbiota transplantation in”
  • body site study.description · “Before and after fecal microbiota transplantation in”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SRR12326881health_conditionulcerative_colitisR40.50study.titleulcerative colitis patients
SRR12326881health_condition_detailUlcerative colitis patients undergoing FMTR40.50study.titleulcerative colitis patients
SRR12326881subject_idUC02R10.70sample.name_rule:library_nameUC02_2-3M_1
SRR12326881timepoint_label2-3MR10.70sample.name_rule:library_nameUC02_2-3M_1
Sequencing

68 runs over 68 samples · mean 9.70 Gbp per run (median 9.15 Gbp, total 659.59 Gbp; 68 runs with a base count) · layout PAIRED 68 · platform ILLUMINA 68 · models Illumina NovaSeq 6000 (68) · 90% of runs with a Sandpiper profile · first public 2024-07-02

Authors (0)

No author record.

Downloads

PRJNA647221.csv.gz (2.3 KB) · parquet (71.4 KB) — all 68 samples, every field with route and confidence · PRJNA647221_determinations.csv.gz (2.5 KB) — 272 evidence rows

Samples (68 · every field this project has values for · hover a cell for its source)
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