Gut-muscle axis in primary sarcopenia, Italy
Shotgun metagenomics of 17 human fecal samples from adults in Italy, exploring fecal microbiota composition and function in relation to primary sarcopenia, in a proof-of-concept study. machine-written summary
17 samples · 17 runs · IT · Adult · 2023 · 19.0 Mbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 34 sample values (collection date, country) |
| ✓ Abstract / description | 34 sample values (health condition, health condition detail) |
| ✓ Full text | 51 sample values (antibiotic exposure, location locality, subject id) · PMC7728056 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 17 | 100% | ||||
| country | 17 | 100% | 17 | |||
| health_condition | 17 | 100% | 17 | |||
| subject_id | 17 | 100% | 17 | |||
| antibiotic_exposure | 17 | 100% | 17 | |||
| collection_date | 17 | 100% | 17 | |||
| detailed_location | 17 | 100% | ||||
| health_condition_detail | 17 | 100% | 17 | |||
| location_locality | 17 | 100% | 17 |
- The Gut-Muscle Axis in Older Subjects with Low Muscle Mass and Performance: A Proof of Concept Study Exploring Fecal Microbiota Composition and Function with Shotgun Metagenomics Sequencing. 2020 PMID 33255677 PMC7728056 own_data
Archive description
The gut-muscle axis in primary sarcopenia: a proof of concept study exploring human fecal microbiota composition and function with shotgun metagenomics sequencing
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “The gut -muscle axis in”
- body site study.description · “The gut -muscle axis in”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN16443345 | antibiotic_exposure | no | R3 | 0.70 | paper.body.methods_results | administration of antibiotics in the month before assessment |
| SAMN16443345 | collection_date | 2020-07-14 | R1 | 0.90 | biosample.attribute:collection_date | 2020-07-14 |
| SAMN16443345 | country | IT | R1 | 0.90 | sample.attr.geo_loc_name | Italy |
| SAMN16443345 | health_condition | other_disease | R4 | 0.50 | study.title | primary sarcopenia |
| SAMN16443345 | health_condition_detail | primary sarcopenia | R4 | 0.50 | study.title | primary sarcopenia |
| SAMN16443345 | location_locality | Parma | R3 | 0.70 | paper.body.methods_results | outpatient Frailty Clinic of Geriatric-Rehabilitation Department, Parma University-Hospital |
| SAMN16443345 | subject_id | SAMN16443345 | R3 | 0.75 | design.one_sample_per_subject:fulltext | Finally, on the same day of clinical and nutritional investigations, each patient handed over a 2-g fecal sample |
Sequencing
17 runs over 17 samples · mean 18.6 Mbp per run (median 19.0 Mbp, total 0.32 Gbp; 17 runs with a base count) · layout PAIRED 17 · platform ILLUMINA 17 · models Illumina MiSeq (17) · 0% of runs with a Sandpiper profile · first public 2023-03-11
Authors (0)
No author record.
Downloads
PRJNA669585.csv.gz (1.3 KB) · parquet (70.3 KB) — all 17 samples, every field with route and confidence · PRJNA669585_determinations.csv.gz (1.6 KB) — 119 evidence rows