A longitudinal cohort of 304 stool samples (261 infant, 43 neonate) from healthy infants, profiling the viral-like particle-enriched gut virome; no health conditions other than healthy control reported. machine-written summary
Sequencing depth per sample · this project all projects
Sampling design and relatedness
longitudinal
8 of 8 people sampled more than once (304 samples; median 37, up to 44 per person) · follow-up median 12 mo (max 13 mo) · median interval between samples 6 d(time from age at collection).
Schedule stated by the source: “Each subject sampled at multiple numbered timepoints (e.g. 1,4,6,9,13,20,29,43); exact unit/schedule not stated.”.
Each row is one person (8 shown); dots are samples at days since that person's first sample.
Veillonella 11.7%Bacteroides 10.5%Veillonella_A 7.5%Ruminococcoides 3.8%Intestinibacter 3.7%Haemophilus_D 1.9%Streptococcus 1.8%Puia 1.5%Terrisporobacter 1.3%Bifidobacterium 1.0%Romboutsia 0.9%Flavobacterium 0.8%not assigned to a genus 49.8%other genera 3.8%
Genera, mean relative abundance over 33 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
The virota and its transkingdom interactions in the healthy infant gut. PMID 35320047PMC9060457curated
A meta-analysis of infant gut viromes reveals global patterns in bacteriophage community assembly and functional capacity over the first three years of life. PMID 42315844PMC13434738curated
Details
Archive description
Viral-like particle enriched viromics of healthy infant stool samples.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of infant / toddler by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
hostrun.scientific_name · “Homo sapiens”
body sitestudy.title · “Infant Gut Virome”
life stagestudy.description · “healthy infant stool samples”
Evidence examples (one per field × route)
sample
field
value
route
conf.
source
quote
SAMN17433579
age_at_collection_days
1
R1
0.80
sample.attr.age
1
SAMN17433579
collection_date
2013/2017
R3
0.70
paper.fulltext.methods
Between 2013 and 2017, stool samples
SAMN17433579
country
BE
R3
0.60
paper.fulltext.results
eight healthy Belgian infants
SAMN17433579
delivery_mode
vaginal
R3
0.60
paper.fulltext.methods
All infants were vaginally born
SAMN17433579
health_condition
healthy_control
R4
0.45
study.description
healthy infant stool samples
SAMN17433579
maternal_antibiotics
no
R3
0.60
paper.fulltext.methods
mothers did not take antibiotics during pregnancy or delivery
SAMN17433579
sex
female
R1
0.90
biosample_attr
female
SAMN17433579
subject_id
S003
R1
0.50
biosample_attr
S003
SAMN17433579
timepoint_label
1
R1
0.70
sample.name_rule:sample_alias
S003-1
Sequencing
304 runs over 304 samples · mean 0.70 Gbp per run (median 0.64 Gbp, total 212.52 Gbp; 304 runs with a base count) · layout PAIRED 304 · platform ILLUMINA 304 · models NextSeq 500 (304) · 13% of runs with a Sandpiper profile · first public 2021-05-01