Gut microbiota & probiotic use during Antarctic ship voyage
38 fecal samples from healthy adult members of the 38th Indian Antarctic Expedition, collected at baseline and after a 24-day ship voyage, in an intervention study comparing probiotic versus placebo effects on gut microbiota. machine-written summary
38 samples · 38 runs · IN · Adult · 2021 · 5.37 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 189 sample values (age, lifestyle, sex, subject id, timepoint) |
| ✓ Abstract / description | 76 sample values (country, lifestyle detail) |
| ✓ Full text | 76 sample values (health condition, health condition detail) · PMC8458292 |
| ✓ Supplementary tables | 28 sample values (intervention) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Probiotic (live microorganisms; single strain or mixture) design randomized_controlled_trial · population healthy_control · Probiotic vs placebo during Antarctic ship voyage
“effect of probiotic intervention on gut microbiota” — abstract:34552104 (study level; per-sample arms are in the intervention column below)
longitudinal
18 of 19 people sampled more than once (36 samples; median 2, up to 2 per person) · follow-up median 12 mo (max 12 mo) · median interval between samples 12 mo (time from age at collection). Schedule stated by the source: “stool at day 0 (baseline, T1) and day 25 (T2, end of 24-day voyage)” (time origin: unknown); stated follow-up 24 d.
Each row is one person (4 shown of 18); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 33 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 38 | 100% | ||||
| country | 38 | 100% | 38 | |||
| health_condition | 38 | 100% | 38 | |||
| subject_id | 37 | 97% | 37 | |||
| age_at_collection_days | 38 | 100% | 38 | |||
| health_condition_detail | 38 | 100% | 38 | |||
| lifestyle | 38 | 100% | 38 | |||
| lifestyle_detail | 38 | 100% | 38 | |||
| sex | 38 | 100% | 38 | |||
| timepoint_label | 38 | 100% | 38 | |||
| intervention | 28 | 74% | 28 |
- Probiotics maintain the gut microbiome homeostasis during Indian Antarctic expedition by ship. 2021 PMID 34552104 PMC8458292 own_data
Archive description
Fecal samples were collected during 38th Indian Scientific Expedition to Antarctica from healthy volunteers, to study the gut microbial changes during ship voyage towards Antarctica. The samples were collected at different time points. Samples were analyzed for shotgun sequencing metagenome.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.57. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.description · “Fecal samples were collected”
- life stage study.description · “healthy volunteers, to study the gut microbial changes”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN17492650 | age_at_collection_days | 15330.5 | R1 | 0.85 | sample.attr.age | 42 |
| SAMN17492650 | country | IN | R4 | 0.50 | study.description | 38th Indian Scientific Expedition to Antarctica |
| SAMN17492650 | health_condition | healthy_control | R3 | 0.70 | paper.fulltext.methods | Nineteen Indian healthy members |
| SAMN17492650 | health_condition_detail | healthy volunteers | R3 | 0.70 | paper.fulltext.methods | Nineteen Indian healthy members |
| SAMN17492660 | intervention | placebo | R2 | 0.80 | paper.supp.41598_2021_97890_MOESM1_ESM.xlsx[S5_Alpha_Diversity!Secondary Group] | Secondary Group: PCB |
| SAMN17492650 | lifestyle | extreme_environment | R1 | 0.85 | biosample.attribute:isolate | 38th (ISEA) Expedition members |
| SAMN17492650 | lifestyle_detail | Indian Antarctic Expedition members | R4 | 0.50 | paper.abstract | 38th Indian Antarctic Expedition |
| SAMN17492650 | sex | male | R1 | 0.90 | sample.attr.sex | male |
| SAMN17492651 | subject_id | 03 | R1 | 0.70 | sample.name_rule:library_name | E03T1 |
| SAMN17492650 | timepoint_label | T1 | R1 | 0.70 | sample.name_rule:library_name | E02T1 |
Sequencing
38 runs over 38 samples · mean 5.30 Gbp per run (median 5.37 Gbp, total 201.55 Gbp; 38 runs with a base count) · layout PAIRED 38 · platform ILLUMINA 38 · models HiSeq X Ten (38) · 87% of runs with a Sandpiper profile · first public 2021-01-29 – 2021-02-05
Authors (9)
Srivastava AK first · Rohil V · Bhushan B · Eslavath MR · Gupta H · Chanda S · Kumar B · Varshney R · Ganju L last
Downloads
PRJNA694018.csv.gz (2.0 KB) · parquet (71.8 KB) — all 38 samples, every field with route and confidence · PRJNA694018_determinations.csv.gz (3.5 KB) — 369 evidence rows