Water chlorination and children's gut microbiome, Bangladesh
95 stool samples from children in two low-income urban communities in Bangladesh (Tongi and Dhaka Uddan), studying the impact of automated water chlorination via a cluster randomized controlled trial. machine-written summary
95 samples · 95 runs · BD · Child · 2021 · 11.34 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 95 sample values (country) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Other administered intervention (see intervention_detail) design randomized_controlled_trial · population healthy_control · Automated water chlorination at shared taps vs control
“cluster randomized controlled trial of automated water chlorination” — bioproject.description (study level; per-sample arms are in the intervention column below)
Genera, mean relative abundance over 86 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 0 | 0% | ||||
| country | 95 | 100% | 95 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% |
- (no title) curated
Archive description
Analysis of childrens stool samples collected during a cluster randomized controlled trial of automated water chlorination at shared taps in two low income urban communities in Bangladesh. Stool samples were frozen but not preserved in conservation medium following collection.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of child and infant / toddler by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host study.title · “Children's Gut Microbiomes in Bangladesh”
- body site study.description · “childrens stool samples collected”
- life stage study.title · “Children's Gut Microbiomes”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN18138612 | country | BD | R1 | 0.90 | biosample_attr | Bangladesh: Dhaka Uddan |
Sequencing
95 runs over 95 samples · mean 11.93 Gbp per run (median 11.34 Gbp, total 1,133.59 Gbp; 95 runs with a base count) · layout PAIRED 95 · platform ILLUMINA 95 · models Illumina NovaSeq 6000 (95) · 91% of runs with a Sandpiper profile · first public 2021-09-02
Authors (13)
Montealegre MC first · Greenwood EE · Teichmann L · Nadimpalli ML · Caduff L · Swarthout JM · Nydegger T · Sultana S · Islam MA · Lanza VF · Luby SP · Pickering AJ · Julian TR last
Help complete this project
3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata
Downloads
PRJNA706606.csv.gz (3.1 KB) · parquet (72.7 KB) — all 95 samples, every field with route and confidence · PRJNA706606_determinations.csv.gz (623 B) — 95 evidence rows