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PRJNA722819 SRP315280

Gut virome in alcoholic liver disease vs healthy, Denmark

Gut virome of patients with alcoholic liver disease and healthy individuals

104 fecal viral metagenome samples from Danish patients with alcoholic liver disease and healthy individuals, analyzed in a case-control design. machine-written summary

104 samples · 104 runs · DK · Adult · 2021 · 1.73 Gbp / sample · cohort A Previously Undescribed Highly Prevalent Phage Id

Sources
✓Sequence archive 832○Abstract / description○Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive832 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude, subject id)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC11792537, PMC11986028, PMC8525569
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult104
Condition
healthy_control52
liver_disease52
Country
DK104
Body site
unknown104
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 19 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 61 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 24 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.73 Gbp per sample0130Gbp
Community composition
Bacteroides 5.5%Ruminococcoides 5.1%Prevotella 4.7%Alistipes 2.9%Roseburia 2.7%Faecalibacterium 2.4%Phocaeicola 2.0%CAG-217 1.6%Intestinibacter 1.4%Ruminococcus_C 1.2%Ruminiclostridium_E 1.2%Fimenecus 1.1%not assigned to a genus 45.4%other genera 22.7%

Genera, mean relative abundance over 74 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category104 100%
country104 100%104
health_condition104 100%104
subject_id104 100%104
collection_date104 100%104
detailed_location104 100%
health_condition_detail104 100%104
latitude104 100%104
location_region104 100%104
longitude104 100%104
Papers (3)
  • A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog. 2021 PMID 34665009 PMC8525569 unsure
  • Identification and characterization of <i>Faecalibacterium</i> prophages rich in diversity-generating retroelements. 2025 PMID 39745426 PMC11792537 unsure
  • Characterization of the phyllosphere virome of fresh vegetables and potential transfer to the human gut. 2025 PMID 40210629 PMC11986028 unsure
Details
Archive description

Fecal viral metagenomes from Danish patients with alcoholic liver disease and healthy individuals.

How this project entered the registry

Classified as human gut / stool / blood / tissue / internal fluids shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Gut virome of patients”
  • body site study.description · “Fecal viral metagenomes from”
  • body site study.title · “patients with alcoholic liver disease and healthy”
  • body site study.description · “patients with alcoholic liver disease and healthy”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN18794141collection_date2021-04-12R10.90biosample.attribute:collection_date2021-04-12
SAMN18794141countryDKR10.90sample.attr.geo_loc_nameDenmark
SAMN18794141health_conditionliver_diseaseR10.70sample.name_rule:aliasCLD001
SAMN18794141health_condition_detailCLDR10.70sample.name_rule:aliasCLD001
SAMN18794141latitude55.3900R10.90biosample.attribute:lat_lon55.39 N 10.37 E
SAMN18794141location_regionSouth DenmarkR10.60biosample.attribute:lat_lon55.39 N 10.37 E
SAMN18794141longitude10.3700R10.90biosample.attribute:lat_lon55.39 N 10.37 E
SAMN18794141subject_idCLD001R10.85sample.attr.subjectCLD001
Sequencing

104 runs over 104 samples · mean 2.20 Gbp per run (median 1.73 Gbp, total 228.29 Gbp; 104 runs with a base count) · layout PAIRED 104 · platform ILLUMINA 104 · models NextSeq 500 (104) · 74% of runs with a Sandpiper profile · first public 2021-09-03

Authors (36)

Van Espen L first · Bak EG · Beller L · Close L · Deboutte W · Juel HB · Nielsen T · Sinar D · De Coninck L · Frithioff-Bøjsøe C · Fonvig CE · Jacobsen S · Kjærgaard M · Thiele M · Fullam A · Kuhn M · Holm JC · Bork P · Krag A · Hansen T · Arumugam M · Matthijnssens J last · Gulyaeva A first · Liu L · Garmaeva S · Kruk M · Weersma RK · Harmsen HJM · Zhernakova A last · Park JW first · Yun YE · Cho JA · Yoon SI · In SA · Park EJ · Kim MS last

Downloads

PRJNA722819.csv.gz (3.5 KB) · parquet (74.3 KB) — all 104 samples, every field with route and confidence · PRJNA722819_determinations.csv.gz (6.0 KB) — 832 evidence rows

Samples (104 · every field this project has values for · hover a cell for its source)
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