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PRJNA723467 SRP315794

Gut virome in Danish obese and healthy minors

Gut virome in obese and healthy minors

150 fecal viral metagenome samples from Denmark, comparing obese minors before and after a 1-year diet/lifestyle intervention with healthy minors, using an intervention study design. machine-written summary

150 samples · 150 runs · DK · Child · 2021 · 1.64 Gbp / sample · cohort A Previously Undescribed Highly Prevalent Phage Id

Sources
✓Sequence archive 1,350○Abstract / description○Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,350 sample values (collection date, country, health condition, health condition detail, intervention, latitude, location region, longitude)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC11792537, PMC11986028, PMC8525569
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention · arms resolved

before · no interventionbefore · no interventi50 samplesotherother100 samples
single arm: samples before and on the intervention

Controlled / prescribed diet or feeding regimen design single_arm_before_after · population obesity · 1-year lifestyle intervention (diet/exercise) in obese minors

“before and after 1 year of life-style interventions” — bioproject.description (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 sampling locations · 1 country
Age
unknown150
Condition
obesity100
healthy_control50
Country
DK150
Body site
primary150
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 47 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 75 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 28 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.64 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

50 of 100 people sampled more than once (100 samples; median 2, up to 2 per person). Schedule stated by the source: “Obese minors sampled before and after 1-year lifestyle intervention (OM vs OM...B pairs); healthy minors (HM) sampled once” (time origin: intervention_start); stated follow-up 12 mo.

How longitudinal and relatedness information is derived

Community composition
Prevotella 12.2%Bacteroides 6.7%Ruminococcoides 6.2%Faecalibacterium 5.5%Alistipes 5.1%CAG-302 2.5%Phocaeicola 2.3%Ruminococcus_C 2.3%Vescimonas 2.3%Roseburia 2.0%CAG-217 1.9%CAG-628 1.4%not assigned to a genus 26.4%other genera 23.2%

Genera, mean relative abundance over 96 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country150 100%150
health_condition150 100%150
subject_id150 100%150
collection_date150 100%150
detailed_location150 100%
health_condition_detail150 100%150
intervention150 100%150
latitude150 100%150
location_region150 100%150
longitude150 100%150
Papers (3)
  • A Previously Undescribed Highly Prevalent Phage Identified in a Danish Enteric Virome Catalog. 2021 PMID 34665009 PMC8525569 unsure
  • Identification and characterization of <i>Faecalibacterium</i> prophages rich in diversity-generating retroelements. 2025 PMID 39745426 PMC11792537 unsure
  • Characterization of the phyllosphere virome of fresh vegetables and potential transfer to the human gut. 2025 PMID 40210629 PMC11986028 unsure
Details
Archive description

Fecal viral metagenomes of Danish obese minors before and after 1 year of life-style interventions and healthy minors

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of child and adolescent by opus_adjudicated with confidence 0.60. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.description · “Fecal viral metagenomes”
  • life stage study.title · “obese and healthy minors”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN18819038collection_date2021-04-12R10.90biosample.attribute:collection_date2021-04-12
SAMN18819038countryDKR10.90sample.attr.geo_loc_nameDenmark
SAMN18819038health_conditionhealthy_controlR10.70sample.name_rule:sample_aliasHM001
SAMN18819038health_condition_detailHMR10.70sample.name_rule:sample_aliasHM001
SAMN18819038interventionno_interventionR10.70sample.name_rule:sample_aliasHM001
SAMN18819038latitude55.7100R10.90biosample.attribute:lat_lon55.71 N 11.72 E
SAMN18819038location_regionZealandR10.60biosample.attribute:lat_lon55.71 N 11.72 E
SAMN18819038longitude11.7200R10.90biosample.attribute:lat_lon55.71 N 11.72 E
SAMN18819038subject_idHM001R10.70sample.name_rule:sample_aliasHM001
Sequencing

150 runs over 150 samples · mean 1.98 Gbp per run (median 1.64 Gbp, total 297.30 Gbp; 150 runs with a base count) · layout PAIRED 150 · platform ILLUMINA 150 · models NextSeq 500 (150) · 64% of runs with a Sandpiper profile · first public 2021-09-03

Authors (36)

Van Espen L first · Bak EG · Beller L · Close L · Deboutte W · Juel HB · Nielsen T · Sinar D · De Coninck L · Frithioff-Bøjsøe C · Fonvig CE · Jacobsen S · Kjærgaard M · Thiele M · Fullam A · Kuhn M · Holm JC · Bork P · Krag A · Hansen T · Arumugam M · Matthijnssens J last · Gulyaeva A first · Liu L · Garmaeva S · Kruk M · Weersma RK · Harmsen HJM · Zhernakova A last · Park JW first · Yun YE · Cho JA · Yoon SI · In SA · Park EJ · Kim MS last

Downloads

PRJNA723467.csv.gz (4.5 KB) · parquet (75.8 KB) — all 150 samples, every field with route and confidence · PRJNA723467_determinations.csv.gz (9.3 KB) — 1,350 evidence rows

Samples (150 · every field this project has values for · hover a cell for its source)
Loading the sample table…