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PRJNA761454 SRP336077

Gut virome in IBD patients and healthy controls, USA

CCFA virome

Cross-sectional study of 96 gut virome samples from Pennsylvania, USA, comparing 86 samples from IBD (unspecified type) patients to 10 from healthy controls. machine-written summary

86 samples · 96 runs · US · Age unknown · 2021 · 1.38 Gbp / sample

Sources
✓Sequence archive 766–Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive766 sample values (collection date, country, health condition, health condition detail, latitude, location region, longitude, subject id)
– Abstract / descriptionno abstract or project description
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown86
Condition
ibd_unspecified86
Country
US86
Body site
primary86
Collected 2018–2020
2018: 35 samples2019: 41 samples2020: 2 samples20182020
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 1 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)this project, 0.1–0.3 Gbp: 1 samplesall projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 11 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 71 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 1.43 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal

43 of 43 people sampled more than once (86 samples; median 2, up to 2 per person) · follow-up median 7 mo (max 16 mo) · median interval between samples 7 mo (time from collection dates). Schedule stated by the source: “archive time labels: 01, 02, 03”.

001001: day 0001: day 230004004: day 0004: day 228007007: day 0007: day 222008008: day 0008: day 224010010: day 0010: day 252012012: day 0012: day 98014014: day 0014: day 204015015: day 0015: day 82016016: day 0016: day 168017017: day 0017: day 189018018: day 0018: day 225021021: day 0021: day 281023023: day 0023: day 212024024: day 0024: day 204025025: day 0025: day 183027027: day 0027: day 210028028: day 0028: day 232029029: day 0029: day 251030030: day 0030: day 202034034: day 0034: day 45039039: day 0039: day 87042042: day 0042: day 97045045: day 0045: day 95051051: day 0051: day 166056056: day 0056: day 97068068: day 0068: day 219076076: day 0076: day 28077077: day 0077: day 348096096: day 0096: day 245097097: day 0097: day 218103103: day 0103: day 219104104: day 0104: day 272105105: day 0105: day 292135135: day 0135: day 46184184: day 0184: day 483193193: day 0193: day 1220 d4 mo8 mo12 mo16 mo

Each row is one person (36 shown of 43); dots are samples at days since that person's first sample.

How longitudinal and relatedness information is derived

Community composition
Ruminococcoides 12.4%Bacteroides 12.0%Prevotella 4.4%Megamonas 3.6%Phocaeicola 3.5%Dialister 3.0%Ruminiclostridium_E 2.7%Alistipes 2.4%Neochristensenella 1.9%Faecalibacterium 1.6%Romboutsia 1.6%Eubacterium_R 1.4%not assigned to a genus 41.0%other genera 8.5%

Genera, mean relative abundance over 30 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country86 100%86
health_condition86 100%86
subject_id86 100%86
detailed_location86 100%
health_condition_detail86 100%86
latitude86 100%86
location_region86 100%86
longitude86 100%86
timepoint_label86 100%86
collection_date78 91%78
Details
Archive description

This study focused on the gut virome of IBD patients

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.55. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.description · “gut virome of IBD patients”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN21348987collection_date2018-10-11R10.90biosample.attribute:collection_date2018-10-11
SAMN21348987countryUSR10.90sample.attr.geo_loc_nameUSA:PA
SAMN21348987health_conditionibd_unspecifiedR10.85biosample.attribute:study_groupbasic
SAMN21348987health_condition_detailbasicR10.85biosample.attribute:study_groupbasic
SAMN21348987latitude39.5700R10.90biosample.attribute:lat_lon39.57 N 75.13 W
SAMN21348987location_regionPennsylvaniaR10.75biosample.attribute:geo_loc_nameUSA:PA
SAMN21348987longitude-75.1300R10.90biosample.attribute:lat_lon39.57 N 75.13 W
SAMN21348987subject_id010R10.85sample.attr.subject_id010
SAMN21348987timepoint_label01R10.70sample.name_rule:alias010-01
Sequencing

96 runs over 86 samples · mean 1.24 Gbp per run (median 1.38 Gbp, total 118.62 Gbp; 96 runs with a base count) · layout PAIRED 96 · platform ILLUMINA 96 · models NextSeq 550 (96) · 57% of runs with a Sandpiper profile · first public 2021-09-09

Authors (0)

No author record.

Downloads

PRJNA761454.csv.gz (3.5 KB) · parquet (74.6 KB) — all 86 samples, every field with route and confidence · PRJNA761454_determinations.csv.gz (6.6 KB) — 766 evidence rows

Samples (86 · every field this project has values for · hover a cell for its source)
Loading the sample table…