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PRJNA763908 SRP337515

Gut microbiota of healthy infants in Hangzhou, China

Intestinal flora sequencing of Chinese infants

66 samples from healthy infants in Hangzhou, China, studied longitudinally to characterize intestinal microbiota composition and function during early life. machine-written summary

66 samples · 66 runs · CN · Infant / toddler · 2021 · 7.81 Gbp / sample

Sources
✓Sequence archive 132✓Abstract / description 66–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive132 sample values (collection date, country)
✓ Abstract / description66 sample values (health condition)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown66
Condition
healthy_control66
Country
CN66
Body site
primary66
Collected 2017–2019
2017: 4 samples2018: 39 samples2019: 23 samples20172019
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 63 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 3 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.81 Gbp per sample0130Gbp
Community composition
Bacteroides 29.8%Escherichia 10.0%Klebsiella 9.9%Bifidobacterium 6.7%Phocaeicola 5.7%Veillonella 5.3%Prevotella 4.0%Mediterraneibacter 2.3%Parabacteroides 2.2%Streptococcus 2.1%Clostridium 2.0%Alistipes 1.5%not assigned to a genus 2.6%other genera 15.8%

Genera, mean relative abundance over 60 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country66 100%66
health_condition66 100%66
subject_id0 0%
collection_date66 100%66
Details
Archive description

Herein, we investigated the composition and functional changes of intestinal microbiota in healthy Chinese infants during early life. Microbiota configuration was analyzed using metagenomics sequencing.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by sonnet_x2 with confidence 0.60. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “Intestinal flora sequencing of Chinese infants”
  • life stage study.description · “healthy Chinese infants during early life”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN21462268collection_date2018-09R10.85biosample.attribute:collection_date2018-09
SAMN21462268countryCNR10.90biosample_attrChina:Hangzhou
SAMN21462268health_conditionhealthy_controlR40.45study.descriptionhealthy Chinese infants during early life
Sequencing

66 runs over 66 samples · mean 7.94 Gbp per run (median 7.81 Gbp, total 523.92 Gbp; 66 runs with a base count) · layout PAIRED 66 · platform ILLUMINA 66 · models Illumina NovaSeq 6000 (66) · 91% of runs with a Sandpiper profile · first public 2021-09-18 – 2021-09-19

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA763908.csv.gz (2.7 KB) · parquet (72.3 KB) — all 66 samples, every field with route and confidence · PRJNA763908_determinations.csv.gz (1.7 KB) — 198 evidence rows

Samples (66 · every field this project has values for · hover a cell for its source)
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