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PRJNA770101 SRP340756

Probio-M9 mother-to-infant transmission, Huhhot, China

the transmission of probio-m9 from mother to infant

71 samples from a nonrandomized intervention study in Huhhot, China, examining transmission of the probiotic Probio-M9 from mother to infant. machine-written summary

71 samples · 71 runs · CN · Infant / toddler · 2022 · 10.81 Gbp / sample

Sources
✓Sequence archive 364○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive364 sample values (collection date, country, family role, intervention, sex, subject id)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Interventions

intervention — arms not resolved

Probiotic (live microorganisms; single strain or mixture) design single_arm_before_after · population pregnancy_postpartum · Probio-M9 probiotic given to mothers, transmission to infant studied

“transmission of probio-m9 from mother to infant” — study.title (study level; per-sample arms are in the intervention column below)

Samples at a glance
1 country
Age
unknown71
Sex
male40
Country
CN71
Body site
primary71
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 4 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 67 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.81 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolvedmother–infant — not resolved

4 of 4 people sampled more than once (71 samples; median 18, up to 20 per person).

Mothers (40 samples, token M) and children (31 samples, token C) for Probio-M9 mother-to-infant transmission; A/B and dyad numbering undocumented.

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 19.7%Bacteroides 18.4%Phocaeicola 5.0%Mediterraneibacter 4.5%Faecalibacterium 3.9%Roseburia 3.6%Klebsiella 3.5%Ruminococcoides 2.2%Alistipes 2.0%Lachnospira 1.7%CAG-302 1.7%CAG-269 1.2%not assigned to a genus 2.6%other genera 29.8%

Genera, mean relative abundance over 66 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country71 100%71
health_condition0 0%
subject_id71 100%71
collection_date71 100%71
family_role71 100%71
intervention40 56%40
sex40 56%40
Details
Archive description

the transmission of probio-m9 from mother to infant

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of infant / toddler by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage verdict include”
  • body site external_curation.infant_catalog · “infant triage verdict include (gut/stool scope)”
  • life stage external_curation.infant_catalog · “infant triage verdict include (0-3 y scope)”
  • life stage study.title · “from mother to infant”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN22208719collection_date2020-12-31R10.85biosample.attribute:collection_datecollection_date: 2020-12-31
SAMN22208719countryCNR10.90biosample_attrChina:Huhhot
SAMN22208719family_rolechildR10.60sample.name_rule:library_nameSample_AC11
SAMN22208735interventionprobioticR10.70sample.name_rule:library_namesSample_AM10
SAMN22208735sexmaleR10.70sample.name_rule:library_namesSample_AM10
SAMN22208719subject_idACR10.70sample.name_rule:library_namesSample_AC11
Sequencing

71 runs over 71 samples · mean 11.00 Gbp per run (median 10.81 Gbp, total 781.04 Gbp; 71 runs with a base count) · layout PAIRED 71 · platform ILLUMINA 71 · models Illumina HiSeq 2500 (71) · 93% of runs with a Sandpiper profile · first public 2022-11-02

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, health_condition. Share metadata

Downloads

PRJNA770101.csv.gz (2.5 KB) · parquet (72.4 KB) — all 71 samples, every field with route and confidence · PRJNA770101_determinations.csv.gz (3.4 KB) — 364 evidence rows

Samples (71 · every field this project has values for · hover a cell for its source)
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