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PRJNA778267 SRP350815

Gut microbiota and SARS-CoV-2 antibodies, Hefei, China

Gut microbiota and SARS-CoV-2

Cross-sectional study of 172 samples from Hefei, China, exploring how body features and gut microbiota relate to SARS-CoV-2 antibody production. machine-written summary

172 samples · 172 runs · CN · Age unknown · 2025 · 7.20 Gbp / sample

Sources
✓Sequence archive 860○Abstract / description✓Full text 344○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive860 sample values (collection date, country, latitude, location locality, longitude)
○ Abstract / descriptionread; no usable statement
✓ Full text344 sample values (health condition, health condition detail) · PMC10511961
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown172
Condition
healthy_control172
Country
CN172
Body site
primary172
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 169 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 3 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.20 Gbp per sample0130Gbp
Community composition
Faecalibacterium 16.9%Prevotella 10.8%Megamonas 9.1%Roseburia 7.8%Phocaeicola 6.8%Bacteroides 4.2%Gemmiger 3.1%Dialister 2.8%Bifidobacterium 2.1%Enterocloster 1.8%Escherichia 1.6%Alistipes 1.5%not assigned to a genus 3.8%other genera 27.8%

Genera, mean relative abundance over 171 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country172 100%172
health_condition172 100%172
subject_id0 0%
collection_date172 100%172
detailed_location172 100%
health_condition_detail172 100%172
latitude172 100%172
location_locality172 100%172
longitude172 100%172
Papers (1)
  • Dynamic changes in host immune system and gut microbiota are associated with the production of SARS-CoV-2 antibodies. 2023 PMID 36207022 PMC10511961 own_data
Details
Archive description

Explore the contributions of body feature and gut microbiota on SARS-CoV-2 antibodies production

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome”
  • body site study.title · “Gut microbiota and SARS-CoV-2”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN23287425collection_date2021-06R10.90biosample.attribute:collection_date2021-06
SAMN23287425countryCNR10.90sample.attr.geo_loc_nameChina:Hefei
SAMN23287425health_conditionhealthy_controlR30.70paper.body.methods_resultsMH, WJ and SH recruited the healthy volunteers from School of Life Sciences, Anhui Medical University
SAMN23287425health_condition_detailhealthy volunteersR30.70paper.body.methods_resultsMH, WJ and SH recruited the healthy volunteers from School of Life Sciences, Anhui Medical University
SAMN23287425latitude31.0000R10.90biosample.attribute:lat_lon31 N 117 E
SAMN23287425location_localityHefeiR10.85biosample.attribute:geo_loc_nameChina:Hefei
SAMN23287425longitude117.0000R10.90biosample.attribute:lat_lon31 N 117 E
Sequencing

172 runs over 172 samples · mean 7.43 Gbp per run (median 7.20 Gbp, total 1,277.11 Gbp; 172 runs with a base count) · layout PAIRED 172 · platform ILLUMINA 172 · models HiSeq X Ten (172) · 99% of runs with a Sandpiper profile · first public 2025-12-21

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA778267.csv.gz (4.6 KB) · parquet (76.1 KB) — all 172 samples, every field with route and confidence · PRJNA778267_determinations.csv.gz (6.7 KB) — 1,204 evidence rows

Samples (172 · every field this project has values for · hover a cell for its source)
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