Gut microbiota in rural vs urban children, Guangdong, China
Cross-sectional study of 1 sample from children in Guangdong, China, examining gut microbiota in relation to rural/urban environmental exposure and allergic disease susceptibility. machine-written summary
65 samples · 65 runs · Age unknown · 2022 · 2.28 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ○ Sequence archive | records read; no usable sample values |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC9542937 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet · share metadata |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
design observational_with_procedure · Intranasal rural/urban dust extracts and FMT from dust-exposed donor mice
Genera, mean relative abundance over 1 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 65 | 100% | ||||
| country | 0 | 0% | ||||
| health_condition | 0 | 0% | ||||
| subject_id | 0 | 0% |
- Rural environment reduces allergic inflammation by modulating the gut microbiota. 2022 PMID 36193874 PMC9542937 own_data
Archive description
In this study, we assessed how rural and urban environmental exposures, particularly indoor dust microbiota, shape gut microbiota and related differential allergy susceptibility, both in humans and in a mouse model of ovalbumin-induced allergic airway inflammation.
How this project entered the registry
Classified as human and non-human (mixed) gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.50. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- host study.description · “mouse model of ovalbumin-induced allergic airway inflammation”
- body site run.scientific_name · “gut metagenome”
Sequencing
65 runs over 65 samples · mean 2.29 Gbp per run (median 2.28 Gbp, total 149.12 Gbp; 65 runs with a base count) · layout PAIRED 65 · platform ILLUMINA 65 · models Illumina HiSeq 4000 (65) · 89% of runs with a Sandpiper profile · first public 2022-09-21
Authors (24)
Yang Z first · Chen Z · Lin X · Yao S · Xian M · Ning X · Fu W · Jiang M · Li N · Xiao X · Feng M · Lian Z · Yang W · Ren X · Zheng Z · Zhao J · Wei N · Lu W · Roponen M · Schaub B · Wong GWK · Su Z · Wang C · Li J last
Help complete this project
3 of the 4 core fields are below 50% coverage: country, health_condition, subject_id. Share metadata
Downloads
PRJNA786015.csv.gz (2.1 KB) · parquet (70.7 KB) — all 65 samples, every field with route and confidence · PRJNA786015_determinations.csv.gz (168 B) — 0 evidence rows