Exercise & gut microbiome in obese older adults
48 gut microbiome samples from overweight/obese older adults (elderly and adult age categories), studying effects of a 12-week exercise intervention (HIIT vs MICT) in an intervention design. machine-written summary
48 samples · 48 runs · Adult · 2022 · 4.18 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 360 sample values (age, health condition, health condition detail, intervention, intervention detail, sex, subject id, timepoint) |
| ○ Abstract / description | read; no usable statement |
| – Full text | no open-access full text linked |
| – Supplementary tables | no supplementary tables available (or none open access) |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention · arms resolved
19 people have samples in more than one arm.
Exercise / physical-training programme design randomized_controlled_trial · population obesity · 12 weeks HIIT vs MICT exercise training
“12 weeks of high-intensity interval training” — bioproject.description (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
24 of 24 people sampled more than once (48 samples; median 2, up to 2 per person).
Genera, mean relative abundance over 38 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 48 | 100% | ||||
| country | 0 | 0% | ||||
| health_condition | 48 | 100% | 48 | |||
| subject_id | 48 | 100% | 48 | |||
| age_at_collection_days | 48 | 100% | 48 | |||
| health_condition_detail | 48 | 100% | 48 | |||
| intervention | 48 | 100% | 48 | |||
| intervention_detail | 48 | 100% | 48 | |||
| sex | 48 | 100% | 48 | |||
| timepoint_label | 24 | 50% | 24 |
Archive description
We compared the effects of 12 weeks of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on physical fitness and gut microbiome in overweight and obese older adults.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult and elderly by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_unknown_no_evidence”
- body site study.title · “continuous training on gut microbiome in overweight”
- body site study.description · “physical fitness and gut microbiome in overweight”
- life stage study.title · “and obese older adults”
- life stage study.description · “and obese older adults .”
- life stage study.title · “overweight and obese older adults”
- life stage study.description · “overweight and obese older adults .”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN24014832 | age_at_collection_days | 24471.8 | R1 | 0.70 | sample.attr.age | 67 |
| SAMN24014832 | health_condition | obesity | R1 | 0.85 | biosample.attribute:isolate | overweight or obese eldly |
| SAMN24014832 | health_condition_detail | overweight or obese eldly | R1 | 0.85 | biosample.attribute:isolate | overweight or obese eldly |
| SAMN24014832 | intervention | no_intervention | R1 | 0.80 | biosample.attribute:treatment | treatment: preCON1 |
| SAMN24014832 | intervention_detail | baseline, non-exercising control group | R1 | 0.80 | biosample.attribute:treatment | treatment: preCON1 |
| SAMN24014832 | sex | male | R1 | 0.90 | sample.attr.sex | male |
| SAMN24014832 | subject_id | CON1 | R1 | 0.70 | sample.name_rule:treatment | preCON1 |
| SAMN24014856 | timepoint_label | post | R1 | 0.70 | sample.name_rule:treatment | endCON1 |
Sequencing
48 runs over 48 samples · mean 4.15 Gbp per run (median 4.18 Gbp, total 199.19 Gbp; 48 runs with a base count) · layout PAIRED 48 · platform ILLUMINA 48 · models HiSeq X Ten (48) · 79% of runs with a Sandpiper profile · first public 2022-06-23
Authors (0)
No author record.
Downloads
PRJNA788670.csv.gz (2.3 KB) · parquet (71.8 KB) — all 48 samples, every field with route and confidence · PRJNA788670_determinations.csv.gz (4.0 KB) — 360 evidence rows