Gut microbiota and probiotic TWK10 in healthy adults, Taiwan
86 gut metagenome samples from healthy adult controls in Taiwan, studying a randomized intervention with viable or heat-killed Lactiplantibacillus plantarum TWK10 probiotic on exercise performance and gut microbiota. machine-written summary
86 samples · 86 runs · TW · Age unknown · 2022 · 65.9 Mbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 398 sample values (collection date, country, intervention, latitude, longitude) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 258 sample values (health condition, health condition detail, location site) · PMC9692508 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Probiotic (live microorganisms; single strain or mixture) design randomized_controlled_trial · population healthy_control · Viable vs heat-killed L. plantarum TWK10, 6 weeks, 3x10^11 CFU/day
“randomly divided into three groups: Control, TWK10” — abstract:36363775 (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
Schedule stated by the source: “Fecal samples collected on last day of 2-week washout (baseline) and after 6-week administration period; alias tokens '-A'/'-B' likely denote these two timepoints per subject.”; stated follow-up 42 d.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 86 | 100% | ||||
| country | 86 | 100% | 86 | |||
| health_condition | 86 | 100% | 86 | |||
| subject_id | 0 | 0% | ||||
| collection_date | 86 | 100% | 86 | |||
| detailed_location | 86 | 100% | ||||
| health_condition_detail | 86 | 100% | 86 | |||
| latitude | 86 | 100% | 86 | |||
| location_site | 86 | 100% | 86 | |||
| longitude | 86 | 100% | 86 | |||
| intervention | 54 | 63% | 54 |
- Different Impacts of Heat-Killed and Viable Lactiplantibacillus plantarum TWK10 on Exercise Performance, Fatigue, Body Composition, and Gut Microbiota in Humans. 2022 PMID 36363775 PMC9692508 own_data
Archive description
Different impact of heat-inactivated and viable Lactobacillus (Lactiplantibacillus) plantarum TWK10 on exercise performance.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.60. Assay shotgun_dna.
- host study.title · “human gut microbial diversity”
- body site study.title · “human gut microbial diversity”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN24255791 | collection_date | 2019-12-05 | R1 | 0.90 | biosample.attribute:collection_date | 2019-12-05 |
| SAMN24255791 | country | TW | R1 | 0.90 | sample.attr.geo_loc_name | Taiwan |
| SAMN24255791 | health_condition | healthy_control | R3 | 0.70 | paper.fulltext.methods | A total of 53 healthy subjects |
| SAMN24255791 | health_condition_detail | healthy subjects without professional athletic training | R3 | 0.70 | paper.fulltext.methods | A total of 53 healthy subjects |
| SAMN24255791 | intervention | placebo | R1 | 0.70 | sample.name_rule:alias | Placebo-A, replicate 1 |
| SAMN24255791 | latitude | 22.8274 | R1 | 0.90 | biosample.attribute:lat_lon | 22.82744260 N 120.27501881 E |
| SAMN24255791 | location_site | Landseed International Hospital | R3 | 0.70 | paper.fulltext.methods | Institutional Review Board of Landseed International Hospital |
| SAMN24255791 | longitude | 120.2750 | R1 | 0.90 | biosample.attribute:lat_lon | 22.82744260 N 120.27501881 E |
Sequencing
86 runs over 86 samples · mean 66.7 Mbp per run (median 65.9 Mbp, total 5.74 Gbp; 86 runs with a base count) · layout PAIRED 86 · platform ILLUMINA 86 · models Illumina MiSeq (86) · 0% of runs with a Sandpiper profile · first public 2022-12-22
Authors (8)
Lee CC first · Liao YC · Lee MC · Cheng YC · Chiou SY · Lin JS · Huang CC · Watanabe K last
Downloads
PRJNA791018.csv.gz (2.8 KB) · parquet (73.8 KB) — all 86 samples, every field with route and confidence · PRJNA791018_determinations.csv.gz (5.5 KB) — 656 evidence rows