Home › Studies › PRJNA797846
PRJNA797846 SRP355321

Intestinal mucosa microbiome in IBD patients, Kunming, China

Intestinal mucosa microbiome (100) and transcriptome (23)

100 intestinal mucosa samples from a case-control study in Kunming, China, comparing ulcerative colitis and Crohn's disease patients with controls to examine links between mucosal bacteria and host autophagy/ER stress/bile acid signaling. machine-written summary

100 samples · 100 runs · CN · Age unknown · 2023 · 27.6 Mbp / sample

Sources
✓Sequence archive 500○Abstract / description✓Full text 200○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive500 sample values (collection date, country, latitude, location locality, longitude)
○ Abstract / descriptionread; no usable statement
✓ Full text200 sample values (antibiotic exposure, location site) · PMC9178242
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown100
Country
CN100
Body site
primary100
Collected 2018–2019
2018: 59 samples2019: 41 samples20182019
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 60 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)this project, 0.03–0.1 Gbp: 40 samplesall projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 0.03 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country100 100%100
health_condition0 0%
subject_id0 0%
antibiotic_exposure100 100%100
collection_date100 100%100
detailed_location100 100%
latitude100 100%100
location_locality100 100%100
location_site100 100%100
longitude100 100%100
Papers (1)
  • Mucosa-Colonizing Microbiota Correlate With Host Autophagy Signaling in Patients With Inflammatory Bowel Disease. 2022 PMID 35694307 PMC9178242 own_data
Details
Archive description

the interaction between bacteria and human gene

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.57. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site study.title · “Intestinal mucosa microbiome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN25038443antibiotic_exposurenoR30.60paper.fulltext.resultsantibiotic use within the last 3 months
SAMN25038443collection_date2018-08-01R10.90biosample.attribute:collection_date2018-08-01
SAMN25038443countryCNR10.90sample.attr.geo_loc_nameChina: Kunming
SAMN25038443latitude25.0300R10.90biosample.attribute:lat_lon25.03 N 102.70 E
SAMN25038443location_localityKunmingR10.85biosample.attribute:geo_loc_nameChina: Kunming
SAMN25038443location_siteFirst People's Hospital of Yunnan ProvinceR30.70paper.fulltext.methodsrecruited from the First People's Hospital of Yunnan Province
SAMN25038443longitude102.7000R10.90biosample.attribute:lat_lon25.03 N 102.70 E
Sequencing

100 runs over 100 samples · mean 27.3 Mbp per run (median 27.6 Mbp, total 2.73 Gbp; 100 runs with a base count) · layout PAIRED 100 · platform ILLUMINA 100 · models Illumina HiSeq 2000 (100) · 0% of runs with a Sandpiper profile · first public 2023-02-02

Authors (9)

Wang W first · Liu Z · Yue W · Zhu L · Zhong H · Yang C · He T · Wan P · Geng J last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA797846.csv.gz (3.1 KB) · parquet (74.0 KB) — all 100 samples, every field with route and confidence · PRJNA797846_determinations.csv.gz (4.5 KB) — 700 evidence rows

Samples (100 · every field this project has values for · hover a cell for its source)
Loading the sample table…