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PRJNA801051 SRP357091

Healthy Chinese gut microbiota across regions and time

Gut microbiota community in healthy Chinese population

239 fecal samples from healthy Chinese adults in Beijing, Henan, Jiangsu, and Sichuan, including a 1-year longitudinal cohort in Beijing, examining spatial and temporal changes in gut microbiota composition. machine-written summary

239 samples · 239 runs · CN · Adult · 2022 · 7.64 Gbp / sample

Sources
✓Sequence archive 759○Abstract / description○Full text○Supplementary tables✓External resources 478–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive759 sample values (collection date, country, location locality, location region, subject id)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC9769860
○ Supplementary tablesfiles read; no table could be matched to the samples
✓ External resources478 sample values (health condition, health condition detail) · from GMrepo v3
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
adult239
Condition
healthy_control239
Country
CN239
Body site
primary239
Collected 2016–2019
2016: 79 samples2017: 58 samples2018: 84 samples2019: 18 samples20162019
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)this project, 0–0.03 Gbp: 1 samplesall projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)this project, 0.3–1 Gbp: 1 samplesall projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 1 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 195 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 41 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.64 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

6 of 7 people sampled more than once (41 samples; median 6, up to 11 per person). Schedule stated by the source: “Cross-sectional collection 2016-2019 across 4 regions; subset of 7 Beijing individuals sampled monthly June 2018-June 2019.”.

How longitudinal and relatedness information is derived

Community composition
Prevotella 23.0%Phocaeicola 16.9%Bacteroides 10.9%Faecalibacterium 5.8%Alistipes 4.7%Roseburia 3.1%Lachnospira 1.6%Acetatifactor 1.3%Sutterella 1.3%Gemmiger 1.2%Hominicoprocola 1.1%Ruminococcoides 1.1%not assigned to a genus 3.4%other genera 24.4%

Genera, mean relative abundance over 222 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category239 100%
country239 100%239
health_condition239 100%239
subject_id42 18%42
collection_date239 100%239
detailed_location239 100%
health_condition_detail239 100%239
location_locality151 63%151
location_region88 37%88
Papers (1)
  • The Spatial Features and Temporal Changes in the Gut Microbiota of a Healthy Chinese Population. 2022 PMID 36453887 PMC9769860 own_data
Details
Archive description

The spatial-temporal change feature of Gut microbiota community in healthy Chinese population

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Gut microbiota community in”
  • body site study.description · “change feature of Gut microbiota community in”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN25290052collection_date2016R10.90biosample.attribute:collection_date2016
SAMN25290052countryCNR10.90sample.attr.geo_loc_nameChina:Beijing
SAMN25290052health_conditionhealthy_controlR20.75external.gmrepo sourcephenotype: Health
SAMN25290052health_condition_detailHealthR20.75external.gmrepo sourcephenotype: Health
SAMN25290052location_localityBeijingR10.85biosample.attribute:geo_loc_nameChina:Beijing
SAMN25290203location_regionHenanR10.85biosample.attribute:geo_loc_nameChina:Henan
SAMN25290075subject_idZY5R10.70sample.name_rule:aliasS18ZYF5
Sequencing

239 runs over 239 samples · mean 8.40 Gbp per run (median 7.64 Gbp, total 2,008.44 Gbp; 239 runs with a base count) · layout PAIRED 239 · platform ILLUMINA 239 · models Illumina HiSeq 2000 (239) · 93% of runs with a Sandpiper profile · first public 2022-04-17 – 2022-10-02

Authors (7)

Zhang W first · Han N · Zhang T · Qiang Y · Peng X · Li X · Kan B last

Downloads

PRJNA801051.csv.gz (6.3 KB) · parquet (78.4 KB) — all 239 samples, every field with route and confidence · PRJNA801051_determinations.csv.gz (9.3 KB) — 1,237 evidence rows

Samples (239 · every field this project has values for · hover a cell for its source)
Loading the sample table…