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PRJNA801067 SRP359485

Gut microbiota in T2DM patients with CAD risk, Zhengzhou

Feces Raw sequence reads

134 fecal samples from adults with type 2 diabetes mellitus in Zhengzhou, China, studied in a case-control design to examine gut microbiota links to coronary artery disease risk. machine-written summary

134 samples · 134 runs · CN · Adult · 2026 · 12.53 Gbp / sample

Sources
✓Sequence archive 536✓Abstract / description 268–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive536 sample values (country, latitude, location locality, longitude)
✓ Abstract / description268 sample values (health condition, health condition detail)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
2 sampling locations · 1 country
Age
adult134
Condition
type2_diabetes134
Country
CN134
Body site
primary134
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 3 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 131 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 12.53 Gbp per sample0130Gbp
Community composition
Prevotella 19.6%Phocaeicola 16.2%Bacteroides 13.1%Faecalibacterium 5.1%Alistipes 4.3%Escherichia 2.3%Parabacteroides 2.1%Roseburia 1.8%Hominicoprocola 1.2%Akkermansia 1.2%Megamonas 1.1%Ruminococcoides 1.0%not assigned to a genus 3.2%other genera 27.8%

Genera, mean relative abundance over 132 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category134 100%
country134 100%134
health_condition134 100%134
subject_id0 0%
detailed_location134 100%
health_condition_detail134 100%134
latitude134 100%134
location_locality134 100%134
longitude134 100%134
Details
Archive description

Type 2 diabetes mellitus(T2DM) is closely associated with atherosclerotic cardiovascular disease. In this study, the gut microbiota and its metabolites were used to analyze the possible mechanism of coronary artery disease (CAD) in T2DM, and to establish a predictive model for CAD in T2DM patients.

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Feces Raw sequence reads”
  • body site study.description · “this study, the gut microbiota and its”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN25291031countryCNR10.90sample.attr.geo_loc_nameChina: Zhengzhou
SAMN25291031health_conditiontype2_diabetesR40.50study.descriptionType 2 diabetes mellitus(T2DM) is closely associated
SAMN25291031health_condition_detailType 2 diabetes mellitusR40.50study.descriptionType 2 diabetes mellitus(T2DM) is closely associated
SAMN25291031latitude34.8000R10.90biosample.attribute:lat_lon34.80 N 113.66 E
SAMN25291031location_localityZhengzhouR10.85biosample.attribute:geo_loc_nameChina: Zhengzhou
SAMN25291031longitude113.6600R10.90biosample.attribute:lat_lon34.80 N 113.66 E
Sequencing

134 runs over 134 samples · mean 12.70 Gbp per run (median 12.53 Gbp, total 1,701.23 Gbp; 134 runs with a base count) · layout PAIRED 134 · platform ILLUMINA 134 · models Illumina NovaSeq 6000 (134) · 99% of runs with a Sandpiper profile · first public 2026-02-22

Authors (0)

No author record.

Downloads

PRJNA801067.csv.gz (3.9 KB) · parquet (74.6 KB) — all 134 samples, every field with route and confidence · PRJNA801067_determinations.csv.gz (4.3 KB) — 804 evidence rows

Samples (134 · every field this project has values for · hover a cell for its source)
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