Gut mycobiome-bacteriome in lung cancer patients, Hungary
86 stool samples from adult, elderly, and neonate lung cancer patients in Hungary, studying bacteriome-mycobiome interactions and Candida overgrowth in a case-control design. machine-written summary
86 samples · 86 runs · HU · Adult · 2023 · 7.77 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 771 sample values (age, bmi, collection date, country, latitude, location region, longitude, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 172 sample values (health condition, health condition detail) · PMC10169812, PMC13319499 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
age: sequence archive and supplementary table disagree for 3 samples (e.g. 0.0 vs 19724) — withheld.
The sources disagree on 3 samples. Where two incompatible values exist for one sample (or one person's samples disagree on sex), neither value is published: the field is left empty here, in the sample sheet and in the downloads. Both sides, with their sources, are in gut_metadata_contradictions.parquet of the data package (what counts as a contradiction).
Contradicted values (3)
| sample | field | value | other value | handling |
|---|---|---|---|---|
| SAMN26340340 | age | 0.0 (sequence archive) | 19724 (supplementary table) | withheld: neither value published |
| SAMN26340376 | age | 0.0 (sequence archive) | 25202 (supplementary table) | withheld: neither value published |
| SAMN26340380 | age | 0.0 (sequence archive) | 23376 (supplementary table) | withheld: neither value published |
Genera, mean relative abundance over 80 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 86 | 100% | ||||
| country | 86 | 100% | 86 | |||
| health_condition | 86 | 100% | 86 | |||
| subject_id | 86 | 100% | 86 | |||
| bmi | 86 | 100% | 86 | |||
| collection_date | 86 | 100% | 86 | |||
| detailed_location | 86 | 100% | ||||
| health_condition_detail | 86 | 100% | 86 | |||
| latitude | 86 | 100% | 86 | |||
| location_region | 86 | 100% | 86 | |||
| longitude | 86 | 100% | 86 | |||
| sex | 86 | 100% | 86 | |||
| age_at_collection_days | 83 | 97% | 83 |
- Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions. 2023 PMID 37160893 PMC10169812 own_data
- The gut mycobiome and inter-kingdom microbial networks are linked to COPD severity in lung cancer patients. 2026 PMID 42062386 PMC13319499 own_data
- The Gut Mycobiome and Inter-kingdom Microbial Networks are linked to COPD Severity in Lung Cancer Patients 2025 own_data
Archive description
Investigating Bacteriome and Mycobiome interactions, and their contribution to lung cancer treatment. For treatment, anti-cancer combination therapy was used.
How this project entered the registry
Classified as human gut / stool / lower respiratory shotgun DNA metagenome of adult and elderly by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “whole metagenomics from stool of human lung”
- body site external_curation.infant_catalog · “body_site_call gut”
- body site study.title · “stool of human lung cancer patients from”
- body site study.description · “their contribution to lung cancer treatment. For”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- life stage sample.attr.age · “70 (n=41/86)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN26340328 | age_at_collection_days | 23741.2 | R1 | 0.70 | sample.attr.age | 65 |
| SAMN26340328 | bmi | 35.0 | R1 | 0.90 | sample.attr.bmi | 35 |
| SAMN26340328 | collection_date | 2018-05-02 | R1 | 0.90 | biosample.attribute:collection_date | 2018-05-02 |
| SAMN26340328 | country | HU | R1 | 0.90 | sample.attr.geo_loc_name | Hungary |
| SAMN26340328 | health_condition | other_cancer | R3 | 0.70 | paper.fulltext.methods | Stage IIIB/IV NSCLC |
| SAMN26340328 | health_condition_detail | advanced lung cancer (NSCLC and other histologies) | R3 | 0.70 | paper.fulltext.methods | Stage IIIB/IV NSCLC |
| SAMN26340328 | latitude | 47.4979 | R1 | 0.90 | biosample.attribute:lat_lon | 47.497913 N 19.040236 E |
| SAMN26340328 | location_region | Budapest | R1 | 0.60 | biosample.attribute:lat_lon | 47.497913 N 19.040236 E |
| SAMN26340328 | longitude | 19.0402 | R1 | 0.90 | biosample.attribute:lat_lon | 47.497913 N 19.040236 E |
| SAMN26340328 | sex | male | R1 | 0.90 | sample.attr.sex | male |
| SAMN26340328 | subject_id | MK110 | R1 | 0.85 | biosample.attribute:alias | MK110 |
Sequencing
86 runs over 86 samples · mean 7.80 Gbp per run (median 7.77 Gbp, total 670.69 Gbp; 86 runs with a base count) · layout PAIRED 86 · platform ILLUMINA 86 · models Illumina HiSeq 2500 (86) · 93% of runs with a Sandpiper profile · first public 2023-03-19
Authors (24)
Seelbinder B first · Lohinai Z · Vazquez-Uribe R · Brunke S · Chen X · Mirhakkak M · Lopez-Escalera S · Dome B · Megyesfalvi Z · Berta J · Galffy G · Dulka E · Wellejus A · Weiss GJ · Bauer M · Hube B · Sommer MOA · Panagiotou G last · Szklenarik G first · Dora D · Szincsak S · Acquah CK · Biswas A · Horváth M
Downloads
PRJNA811494.csv.gz (3.9 KB) · parquet (75.5 KB) — all 86 samples, every field with route and confidence · PRJNA811494_determinations.csv.gz (7.5 KB) — 943 evidence rows