Home › Studies › PRJNA818062
PRJNA818062 SRP364948

Microbiome in Tibetan adults with coronary heart disease

the gut microbiome metagenomic of Tibetan subjects

45 gut metagenome samples from adult subjects in Qinghai, China, cross-sectional design, comparing healthy controls (27) to individuals with cardiometabolic conditions (18), including coronary heart disease. machine-written summary

45 samples · 45 runs · CN · Adult · 2023 · 12.87 Gbp / sample

Sources
✓Sequence archive 225✓Abstract / description 45–Full text–Supplementary tables✓External resources 90–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive225 sample values (collection date, country, latitude, location region, longitude)
✓ Abstract / description45 sample values (subject id)
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
✓ External resources90 sample values (health condition, health condition detail) · from GMrepo v3
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult45
Condition
healthy_control27
cardiometabolic_other18
Country
CN45
Body site
primary45
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 1 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 44 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 12.87 Gbp per sample0130Gbp
Community composition
Prevotella 15.3%Bacteroides 6.5%Roseburia 6.0%Alistipes 4.7%Faecalibacterium 4.0%Fimenecus 3.2%Bifidobacterium 3.0%Phocaeicola 2.7%Vescimonas 2.0%Gemmiger 2.0%Escherichia 1.9%Ruminococcoides 1.6%not assigned to a genus 3.3%other genera 43.9%

Genera, mean relative abundance over 38 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category45 100%
country45 100%45
health_condition45 100%45
subject_id45 100%45
collection_date45 100%45
detailed_location45 100%
health_condition_detail45 100%45
latitude45 100%45
location_region45 100%45
longitude45 100%45
Papers (1)
  • Structural and functional dysbiosis of gut microbiota in Tibetan subjects with coronary heart disease. 2022 PMID 36115504 own_data
Details
Archive description

Metagenomic analysis reveals the gut microbiome of Tibetan subjects with coronary heart disease

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “the gut microbiome metagenomic of”
  • body site study.description · “analysis reveals the gut microbiome of Tibetan”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN26814870collection_date2018-12-15R10.90biosample.attribute:collection_date2018-12-15
SAMN26814870countryCNR10.90sample.attr.geo_loc_nameChina:Qinghai
SAMN26814870health_conditioncardiometabolic_otherR20.75external.gmrepo sourcephenotype: Coronary Disease
SAMN26814870health_condition_detailCoronary DiseaseR20.75external.gmrepo sourcephenotype: Coronary Disease
SAMN26814870latitude36.3700R10.90biosample.attribute:lat_lon36.37 N 101.44 E
SAMN26814870location_regionQinghaiR10.85biosample.attribute:geo_loc_nameChina:Qinghai
SAMN26814870longitude101.4400R10.90biosample.attribute:lat_lon36.37 N 101.44 E
SAMN26814870subject_idSAMN26814870R40.60design.one_sample_per_subject:abstract14 CHD patients, 13 patients with non-stenosis coronary heart disease (NCHD), and 18 healthy controls (HT)
Sequencing

45 runs over 45 samples · mean 13.18 Gbp per run (median 12.87 Gbp, total 593.16 Gbp; 45 runs with a base count) · layout PAIRED 45 · platform ILLUMINA 45 · models Illumina HiSeq 2000 (45) · 84% of runs with a Sandpiper profile · first public 2023-06-05

Authors (0)

No author record.

Downloads

PRJNA818062.csv.gz (2.1 KB) · parquet (71.7 KB) — all 45 samples, every field with route and confidence · PRJNA818062_determinations.csv.gz (3.2 KB) — 360 evidence rows

Samples (45 · every field this project has values for · hover a cell for its source)
Loading the sample table…