Gut microbiome in low back pain, fatty replacement
Case-control study of 36 gut microbiome samples from adults with chronic low back pain (with or without vertebral fatty replacement) and healthy controls; country not reported. machine-written summary
36 samples · 36 runs · CN · Adult · 2026 · 12.51 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 72 sample values (health condition, health condition detail) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 72 sample values (antibiotic exposure, country) · PMC11772216 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 36 | 100% | ||||
| country | 36 | 100% | 36 | |||
| health_condition | 36 | 100% | 36 | |||
| subject_id | 0 | 0% | ||||
| antibiotic_exposure | 36 | 100% | 36 | |||
| health_condition_detail | 36 | 100% | 36 |
- Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions. 2025 PMID 39877797 PMC11772216 own_data
Archive description
Gut microbiome dysbiosis in low back pain patients with/without modic changes and Healthy controls
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by deterministic_prior with confidence 0.90. Assay shotgun_dna.
- host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
- body site study.title · “Gut microbiome dysbiosis in”
- body site study.description · “Gut microbiome dysbiosis in”
- life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN27361720 | antibiotic_exposure | no | R3 | 0.70 | paper.fulltext.methods | any antibiotics or oral corticosteroids in past 1 month |
| SAMN27361720 | country | CN | R3 | 0.70 | paper.fulltext.methods | sample collection for this collaborative project was exclusively conducted in China |
| SAMN27361720 | health_condition | other_disease | R1 | 0.85 | biosample.attribute:treatment | treatment: LBP+MCs |
| SAMN27361720 | health_condition_detail | LBP+MCs | R1 | 0.85 | biosample.attribute:treatment | treatment: LBP+MCs |
Sequencing
36 runs over 36 samples · mean 12.46 Gbp per run (median 12.51 Gbp, total 448.48 Gbp; 36 runs with a base count) · layout PAIRED 36 · platform ILLUMINA 36 · models Illumina HiSeq 2500 (36) · 0% of runs with a Sandpiper profile · first public 2026-04-19
Authors (14)
Li W first · Tu J · Zheng J · Das A · Yan Q · Jiang X · Ding W · Bai X · Lai K · Yang S · Yang C · Zou J · Diwan AD · Zheng Z last
Downloads
PRJNA822996.csv.gz (1.7 KB) · parquet (70.0 KB) — all 36 samples, every field with route and confidence · PRJNA822996_determinations.csv.gz (1.4 KB) — 144 evidence rows