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PRJNA834885 SRP373496

Gut metagenome of Hong Kong travellers before/after travel

Gut metagenomes of healthy Chinese international travellers

180 stool samples from healthy adult Hong Kong residents, collected before and after international travel, in a longitudinal study of gut microbiome and antibiotic resistance gene changes associated with travel. machine-written summary

180 samples · 180 runs · HK · Adult · 2023 · 6.42 Gbp / sample

Sources
✓Sequence archive 1,768○Abstract / description✓Full text 362○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive1,768 sample values (age, antibiotic exposure, bmi, country, latitude, longitude, sex, smoking status)
○ Abstract / descriptionread; no usable statement
✓ Full text362 sample values (antibiotic exposure, health condition, health condition detail) · PMC10628765
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
adult180
Condition
healthy_control180
Sex
female124
male48
Country
HK180
Body site
primary180
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 180 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.42 Gbp per sample0130Gbp
Sampling design and relatedness

longitudinal — not resolved

90 of 90 people sampled more than once (180 samples; median 2, up to 2 per person). Schedule stated by the source: “Each subject sampled twice: pre-trip and post-trip (before and after international travel)” (time origin: other).

How longitudinal and relatedness information is derived

Community composition
Bifidobacterium 12.9%Blautia_A 11.9%Faecalibacterium 7.5%Roseburia 4.9%Bacteroides 4.8%Fusicatenibacter 4.3%Ruminococcoides 4.1%Phocaeicola 3.8%Mediterraneibacter 3.2%Collinsella 3.2%Anaerostipes 2.5%Gemmiger 2.0%not assigned to a genus 3.9%other genera 31.0%

Genera, mean relative abundance over 164 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category180 100%
country180 100%180
health_condition180 100%180
subject_id180 100%180
antibiotic_exposure180 100%1782
health_condition_detail180 100%180
latitude180 100%180
longitude180 100%180
timepoint_label180 100%180
smoking_status176 98%176
age_at_collection_days174 97%174
sex172 96%172
bmi168 93%168
Papers (1)
  • Alterations in faecal microbiome and resistome in Chinese international travellers: a metagenomic analysis. 2023 PMID 36864573 PMC10628765 own_data
Details
Archive description

To characterise the changes in the gut metagenomes of Chinese international travellers before and after travel

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of adult and adolescent by deterministic_prior with confidence 0.90. Assay shotgun_dna.

  • host external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • body site study.title · “Gut metagenomes of healthy”
  • body site study.description · “changes in the gut metagenomes of Chinese”
  • life stage external_curation.infant_catalog · “infant triage reason_code age_adult_only”
  • life stage sample.attr.age · “19 (n=22/180)”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN28078811age_at_collection_days8034.0R10.85sample.attr.age22
SAMN28078811antibiotic_exposurenoR10.90biosample_attrNo
SAMN28078852antibiotic_exposurenoR30.70paper.fulltext.methodsused antibiotics within last three months before travel
SAMN28078811bmi20.45R10.90sample.attr.bmi20.446742023841672
SAMN28078811countryHKR10.90sample.attr.geo_loc_nameHong Kong
SAMN28078811health_conditionhealthy_controlR30.70paper.fulltext.abstract90 healthy Chinese adult residents of Hong Kong
SAMN28078811health_condition_detailhealthy Chinese adult residentsR30.70paper.fulltext.abstract90 healthy Chinese adult residents of Hong Kong
SAMN28078811latitude22.1800R10.90biosample.attribute:lat_lon22.18 N 114.10 E
SAMN28078811longitude114.1000R10.90biosample.attribute:lat_lon22.18 N 114.10 E
SAMN28078811sexfemaleR10.90sample.attr.sexfemale
SAMN28078811smoking_statusneverR10.80biosample.attribute:smokingNo
SAMN28078811subject_idTRM-C001R10.85sample.attr.subject_numberTRM-C001
SAMN28078811timepoint_labelPre-tripR10.85sample.attr.time_pointPre-trip
Sequencing

180 runs over 180 samples · mean 6.40 Gbp per run (median 6.42 Gbp, total 1,152.71 Gbp; 180 runs with a base count) · layout PAIRED 180 · platform ILLUMINA 180 · models Illumina NovaSeq 6000 (180) · 91% of runs with a Sandpiper profile · first public 2023-03-07

Authors (14)

Cheung MK first · Ng RWY · Lai CKC · Zhu C · Au ETK · Yau JWK · Li C · Wong HC · Wong BCK · Kwok KO · Chen Z · Chan PKS · Lui GCY · Ip M last

Downloads

PRJNA834885.csv.gz (6.2 KB) · parquet (78.5 KB) — all 180 samples, every field with route and confidence · PRJNA834885_determinations.csv.gz (15.9 KB) — 2,130 evidence rows

Samples (180 · every field this project has values for · hover a cell for its source)
Loading the sample table…