Gut microbiome in axial spondyloarthritis: case-control
33 fecal samples from axial spondyloarthritis patients (32 adults, 1 elderly), compared using 16S rRNA sequencing in a case-control design examining gut microbiota differences linked to disease, mostly notably Faecalibacterium prausnitzii abundance. machine-written summary
33 samples · 33 runs · KR · Adult · 2022 · 15.2 Mbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 66 sample values (age, sex) |
| ✓ Abstract / description | 33 sample values (health condition detail) |
| ✓ Full text | 66 sample values (country, subject id) · PMC10152063 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
design observational_with_procedure
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 33 | 100% | ||||
| country | 33 | 100% | 33 | |||
| health_condition | 0 | 0% | ||||
| subject_id | 33 | 100% | 33 | |||
| age_at_collection_days | 33 | 100% | 33 | |||
| health_condition_detail | 33 | 100% | 33 | |||
| sex | 33 | 100% | 33 |
- Identification of gut dysbiosis in axial spondyloarthritis patients and improvement of experimental ankylosing spondyloarthritis by microbiome-derived butyrate with immune-modulating function. 2023 PMID 37143677 PMC10152063 own_data
Archive description
We investigated the difference between the microbiome of Spondyloarthritis patients and healthy
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.65. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site sample.attr.tissue · “Feces (n=33/33)”
- life stage sample.attr.age · “48 (n=32/33)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN30033205 | age_at_collection_days | 16071.0 | R1 | 0.85 | sample.attr.age | 44 |
| SAMN30033205 | country | KR | R3 | 0.70 | paper.fulltext.methods | Seoul Saint Mary’s Hospital and Konkuk University Medical Center (Seoul, South Korea) |
| SAMN30033205 | health_condition_detail | mixed_case_control: Spondyloarthritis patients vs healthy controls | R4 | 0.50 | study.description | Spondyloarthritis patients and healthy |
| SAMN30033205 | sex | female | R1 | 0.90 | sample.attr.sex | female |
| SAMN30033205 | subject_id | SAMN30033205 | R3 | 0.70 | design.one_sample_per_subject:fulltext | A total of 33 axSpA patients and 20 HCs were included. |
Sequencing
33 runs over 33 samples · mean 17.7 Mbp per run (median 15.2 Mbp, total 0.59 Gbp; 33 runs with a base count) · layout PAIRED 33 · platform ILLUMINA 33 · models Illumina HiScanSQ (33) · 0% of runs with a Sandpiper profile · first public 2022-07-31 – 2022-08-28
Authors (15)
Min HK first · Na HS · Jhun J · Lee SY · Choi SS · Park GE · Lee JS · Um IG · Seo H · Shin TS · Kim YK · Lee JJ · Kwok SK · Cho ML · Park SH last
Downloads
PRJNA863406.csv.gz (1.8 KB) · parquet (70.9 KB) — all 33 samples, every field with route and confidence · PRJNA863406_determinations.csv.gz (2.0 KB) — 165 evidence rows