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PRJNA877820 SRP396574

Gut metagenome in childhood type 1 diabetes, China

Metagenomics of gut microbiota

Shotgun metagenomic sequencing of fecal samples from 58 children in China (29 with new-onset type 1 diabetes, 29 healthy controls) collected in January 2018. machine-written summary

58 samples · 58 runs · CN · Age unknown · 2024 · 11.12 Gbp / sample

Sources
✓Sequence archive 232○Abstract / description○Full text○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive232 sample values (collection date, country, health condition, health condition detail)
○ Abstract / descriptionread; no usable statement
○ Full textread; no usable statement or table · PMC9606127
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown58
Condition
healthy_control29
type1_diabetes29
Country
CN58
Body site
primary58
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)all projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 58 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 11.12 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country58 100%58
health_condition58 100%58
subject_id0 0%
collection_date58 100%58
health_condition_detail58 100%58
Papers (1)
  • Functional and metabolic alterations of gut microbiota in children with new-onset type 1 diabetes. 2022 PMID 36289225 PMC9606127 own_data
Details
Archive description

Metagenomics of gut microbiota

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by curator_audit with confidence 0.50. Assay shotgun_dna.

  • host runs.scientific_name · “human gut metagenome (58)”
  • host papers[0].abstract · “gut microbial functional and metabolic alterations”
  • body site runs.scientific_name · “human gut metagenome (58)”
  • body site papers[0].abstract · “gut microbial functional and metabolic alterations”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN30723751collection_date2018-01R10.85biosample.attribute:collection_datecollection_date: 2018-01
SAMN30723751countryCNR10.90sample.attr.geo_loc_nameChina
SAMN30723751health_conditionhealthy_controlR10.70sample.name_rule:experiment_titleexperiment_title: Illumina NovaSeq 6000 sequencing: FJ_1_NC
SAMN30723751health_condition_detailNCR10.70sample.name_rule:experiment_titleexperiment_title: Illumina NovaSeq 6000 sequencing: FJ_1_NC
Sequencing

58 runs over 58 samples · mean 11.30 Gbp per run (median 11.12 Gbp, total 655.38 Gbp; 58 runs with a base count) · layout PAIRED 58 · platform ILLUMINA 58 · models Illumina NovaSeq 6000 (58) · 97% of runs with a Sandpiper profile · first public 2024-10-27

Authors (46)

Rampelli S first · Soverini M · D'Amico F · Barone M · Tavella T · Monti D · Capri M · Astolfi A · Brigidi P · Biagi E · Franceschi C · Turroni S · Candela M last · Yuan X first · Wang R · Han B · Sun C · Chen R · Wei H · Chen L · Du H · Li G · Yang Y · Chen X · Cui L · Xu Z · Fu J · Wu J · Gu W · Chen Z · Fang X · Yang H · Su Z · Li Q · Zhang M · Zhou Y · Zhang L · Ji G · Luo F last · Zhou J first · Zhang Q · Zhao Y · Zou Y · Chen M · Zhou S · Wang Z last

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA877820.csv.gz (2.2 KB) · parquet (70.8 KB) — all 58 samples, every field with route and confidence · PRJNA877820_determinations.csv.gz (2.4 KB) — 232 evidence rows

Samples (58 · every field this project has values for · hover a cell for its source)
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