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PRJNA881732 SRP397884

Gut microbiota in tuberculosis patients, Xinjiang, China

gut metagenome

58 gut metagenome samples from patients with tuberculosis in Xinjiang, China, studying changes in intestinal flora associated with the infection. machine-written summary

58 samples · 58 runs · CN · Age unknown · 2025 · 7.14 Gbp / sample

Sources
✓Sequence archive 290○Abstract / description–Full text–Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive290 sample values (collection date, country, health condition, health condition detail, location region)
○ Abstract / descriptionread; no usable statement
– Full textno open-access full text linked
– Supplementary tablesno supplementary tables available (or none open access)
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown58
Condition
other_infection40
healthy_control18
Country
CN58
Body site
primary58
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 58 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 7.14 Gbp per sample0130Gbp
Community composition
Bifidobacterium 23.8%Collinsella 6.5%Blautia_A 6.2%Gemmiger 5.7%Ruminococcoides 3.6%Faecalibacterium 3.3%Roseburia 2.3%Akkermansia 2.3%Fimenecus 2.1%Streptococcus 1.5%Holdemanella 1.5%Prevotella 1.4%not assigned to a genus 3.8%other genera 36.0%

Genera, mean relative abundance over 58 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country58 100%58
health_condition58 100%58
subject_id0 0%
collection_date58 100%58
detailed_location58 100%
health_condition_detail58 100%58
location_region58 100%58
Details
Archive description

To explore the changes of intestinal flora in patients with tuberculosis

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.60. Assay shotgun_dna.

  • host study.description · “patients with tuberculosis”
  • body site study.description · “changes of intestinal flora”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN30914390collection_date2021-04-03R10.90biosample.attribute:collection_date2021-04-03
SAMN30914390countryCNR10.90sample.attr.geo_loc_nameChina:XinJiang
SAMN30914390health_conditionhealthy_controlR10.70sample.name_rule:aliasHC3
SAMN30914390health_condition_detailHCR10.70sample.name_rule:aliasHC3
SAMN30914390location_regionXinjiangR10.85biosample.attribute:geo_loc_nameChina:XinJiang
Sequencing

58 runs over 58 samples · mean 7.07 Gbp per run (median 7.14 Gbp, total 409.84 Gbp; 58 runs with a base count) · layout PAIRED 58 · platform ILLUMINA 58 · models Illumina NovaSeq 6000 (58) · 100% of runs with a Sandpiper profile · first public 2025-07-01 – 2025-07-27

Authors (0)

No author record.

Help complete this project

2 of the 4 core fields are below 50% coverage: age_category, subject_id. Share metadata

Downloads

PRJNA881732.csv.gz (2.3 KB) · parquet (71.3 KB) — all 58 samples, every field with route and confidence · PRJNA881732_determinations.csv.gz (2.9 KB) — 290 evidence rows

Samples (58 · every field this project has values for · hover a cell for its source)
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