Gut microbiome in OCD before/after ERP therapy
79 stool samples from adults with OCD (before and after exposure- and response prevention therapy) and healthy controls, analyzed longitudinally via whole genome sequencing. machine-written summary
79 samples · 79 runs · SE · Adult · 2023 · 3.63 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 535 sample values (age, bmi, collection date, health condition, health condition detail, intervention, sex) |
| ○ Abstract / description | read; no usable statement |
| ✓ Full text | 158 sample values (antibiotic exposure, location locality) · PMC10454283 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| ✓ External resources | 79 sample values (country) · from GMrepo v3 |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
longitudinal — not resolved
Schedule stated by the source: “stool before ERP and 1 month after completion of ERP” (time origin: intervention_start); stated follow-up 30 d.
No Sandpiper profile for this project's samples yet.
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 79 | 100% | ||||
| country | 79 | 100% | 79 | |||
| health_condition | 79 | 100% | 79 | |||
| subject_id | 0 | 0% | ||||
| age_at_collection_days | 79 | 100% | 79 | |||
| antibiotic_exposure | 79 | 100% | 79 | |||
| collection_date | 79 | 100% | 79 | |||
| detailed_location | 79 | 100% | ||||
| health_condition_detail | 79 | 100% | 79 | |||
| intervention | 79 | 100% | 79 | |||
| location_locality | 79 | 100% | 79 | |||
| sex | 79 | 100% | 79 | |||
| bmi | 61 | 77% | 61 |
- Longitudinal study of gut microbiome in obsessive-compulsive disorder. 2023 PMID 37277984 PMC10454283 own_data
Archive description
Gut microbiome in patients with obsessive-compulsive disorder before and after exposure- and response prevention psycotherapy.
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of adult by sonnet_x2 with confidence 0.62. Assay shotgun_dna.
- host run.scientific_name · “Homo sapiens”
- body site study.title · “gut microbiome in obsessive-compulsive disorder”
- life stage sample.attr.age · “27 (n=72/79)”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN30960026 | age_at_collection_days | 7305.0 | R1 | 0.85 | sample.attr.age | 20 |
| SAMN30960026 | antibiotic_exposure | no | R3 | 0.70 | paper.fulltext.methods | antibiotic use in the past 3 months |
| SAMN30960027 | bmi | 19.8 | R1 | 0.90 | sample.attr.bmi | 19.8 |
| SAMN30960026 | collection_date | 2020-01-01 | R1 | 0.90 | biosample.attribute:collection_date | 2020-01-01 |
| SAMN30960026 | country | SE | R2 | 0.75 | external.gmrepo source | country: Sweden |
| SAMN30960026 | health_condition | healthy_control | R1 | 0.85 | biosample.attribute:isolate | HC |
| SAMN30960026 | health_condition_detail | HC | R1 | 0.85 | biosample.attribute:isolate | HC |
| SAMN30960026 | intervention | no_intervention | R1 | 0.85 | biosample.attribute:isolate | HC |
| SAMN30960026 | location_locality | Stockholm | R3 | 0.70 | paper.fulltext.methods | specialist OCD clinics in Stockholm, Sweden |
| SAMN30960026 | sex | female | R1 | 0.90 | sample.attr.sex | female |
Sequencing
79 runs over 79 samples · mean 3.81 Gbp per run (median 3.63 Gbp, total 300.92 Gbp; 79 runs with a base count) · layout PAIRED 79 · platform COMPLETE_GENOMICS 79 · models Complete Genomics (79) · 0% of runs with a Sandpiper profile · first public 2023-06-21 – 2023-06-22
Downloads
PRJNA883179.csv.gz (3.4 KB) · parquet (74.6 KB) — all 79 samples, every field with route and confidence · PRJNA883179_determinations.csv.gz (6.8 KB) — 772 evidence rows