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PRJNA890567 SRP405584

Metagenome in anemia of chronic renal failure, case-control

gut metagenome for chronic kidney disease

57 gut metagenome samples from a case-control study comparing patients with anemia of chronic renal failure to healthy controls, examining gut microbiota and associated metabolites. machine-written summary

78 samples · 78 runs · CN · Age unknown · 2025 · 10.99 Gbp / sample

Sources
✓Sequence archive 363✓Abstract / description 78✓Full text 42○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive363 sample values (collection date, country, latitude, location locality, location region, longitude)
✓ Abstract / description78 sample values (health condition detail)
✓ Full text42 sample values (collection date, location locality) · PMC12323308
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 sampling locations · 1 country
Age
unknown78
Country
CN78
Body site
primary78
Collected 2020–2021
2020: 57 samples2021: 21 samples20202021
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 5 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 73 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 10.99 Gbp per sample0130Gbp
Community composition
Bacteroides 22.2%Phocaeicola 11.3%Bifidobacterium 5.4%Blautia_A 4.4%Mediterraneibacter 4.0%Escherichia 3.2%Faecalibacterium 2.9%Alistipes 2.7%Roseburia 2.0%Prevotella 2.0%Parabacteroides 1.9%Klebsiella 1.8%not assigned to a genus 2.8%other genera 33.5%

Genera, mean relative abundance over 57 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country78 100%78
health_condition0 0%
subject_id0 0%
collection_date78 100%5721
detailed_location78 100%
health_condition_detail78 100%78
location_locality78 100%5721
latitude57 73%57
location_region57 73%57
longitude57 73%57
Papers (1)
  • Altered fecal microbial and metabolic profiles reveal potential mechanisms underlying anemia in patients with chronic renal failure. 2025 PMID 40525868 PMC12323308 own_data
Details
Archive description

Gut metagenome for chronic kidney disease

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.60. Assay shotgun_dna.

  • host study.title · “gut metagenome for chronic kidney disease”
  • body site study.title · “gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN31475887collection_date2020-07R10.90biosample.attribute:collection_date2020-07
SAMN31475885collection_date2021-06/2021-12R30.70paper.fulltext.methodsrecruited from June 2021 to December 2021
SAMN31475885countryCNR10.90sample.attr.geo_loc_nameChina: Shanghai
SAMN31475885health_condition_detailmixed_case_control: anemia of chronic renal failure vs healthy controlsR40.50paper.abstract30 patients with anemia of CRF and 20 healthy controls
SAMN31475887latitude31.2700R10.90biosample.attribute:lat_lon31.27 N 121.45 E
SAMN31475887location_localityShanghaiR10.85biosample.attribute:geo_loc_nameChina: Shanghai
SAMN31475885location_localityShanghaiR30.70paper.fulltext.methodsShanghai Tenth People's Hospital affiliated with Tongji University, Shanghai, China
SAMN31475887location_regionShanghai ShiR10.60biosample.attribute:lat_lon31.27 N 121.45 E
SAMN31475887longitude121.4500R10.90biosample.attribute:lat_lon31.27 N 121.45 E
Sequencing

78 runs over 78 samples · mean 11.06 Gbp per run (median 10.99 Gbp, total 862.58 Gbp; 78 runs with a base count) · layout PAIRED 78 · platform ILLUMINA 78 · models Illumina NovaSeq 6000 (78) · 100% of runs with a Sandpiper profile · first public 2025-05-08 – 2025-05-28

Authors (9)

Wang H first · Xue W · Cheng J · He Y · Song Y · Hu D · Peng A · Li C · Bao H last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA890567.csv.gz (2.8 KB) · parquet (73.4 KB) — all 78 samples, every field with route and confidence · PRJNA890567_determinations.csv.gz (3.6 KB) — 483 evidence rows

Samples (78 · every field this project has values for · hover a cell for its source)
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