Resistant dextrin fibre intervention in healthy adults
80 fecal shotgun metagenome samples from healthy adults in Barcelona, Spain, in an intervention study on resistant dextrin (NUTRIOSE) soluble fibre supplementation and its effects on gut microbiota composition and intestinal gas production. machine-written summary
80 samples · 80 runs · ES · Age unknown · 2023 · 12.20 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 633 sample values (collection date, country, health condition, health condition detail, intervention, location locality, sex, subject id) |
| ○ Abstract / description | read; no usable statement |
| ○ Full text | read; no usable statement or table · PMC9654059 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention · arms resolved
Prebiotic / dietary fibre supplement design single_arm_before_after · population healthy_control · Resistant dextrin fibre (NUTRIOSE) 14 g/day for 4 weeks
“were given resistant dextrin” — abstract:36364873 (study level; per-sample arms are in the intervention column below)
longitudinal — not resolved
19 of 19 people sampled more than once (76 samples; median 4, up to 4 per person). Schedule stated by the source: “Samples taken before, at beginning, end, and 2 weeks after 4-week resistant dextrin administration (4 timepoints per subject)” (time origin: intervention start); stated follow-up 42 d.
Genera, mean relative abundance over 74 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 80 | 100% | ||||
| country | 80 | 100% | 80 | |||
| health_condition | 79 | 99% | 79 | |||
| subject_id | 76 | 95% | 76 | |||
| collection_date | 80 | 100% | 80 | |||
| detailed_location | 80 | 100% | ||||
| location_locality | 80 | 100% | 80 | |||
| sex | 80 | 100% | 80 | |||
| health_condition_detail | 79 | 99% | 79 | |||
| intervention | 79 | 99% | 79 |
- Effect of Resistant Dextrin on Intestinal Gas Homeostasis and Microbiota. 2022 PMID 36364873 PMC9654059 own_data
Archive description
Shotgun metagenomics sequencing data for the article "Microbiome changes induced by resistant dextrin modulate intestinal gas homeostasis"
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by opus_adjudicated with confidence 0.75. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site study.title · “modulate intestinal gas homeostasis”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN31373368 | collection_date | 2020-11-25 | R1 | 0.90 | biosample.attribute:collection_date | 2020-11-25 |
| SAMN31373368 | country | ES | R1 | 0.90 | sample.attr.geo_loc_name | Spain: Barcelona |
| SAMN31373368 | health_condition | healthy_control | R1 | 0.70 | sample.name_rule:alias | 10_DEX-B |
| SAMN31373368 | health_condition_detail | DEX | R1 | 0.70 | sample.name_rule:alias | 10_DEX-B |
| SAMN31373368 | intervention | prebiotic_or_fibre | R1 | 0.70 | sample.name_rule:alias | 10_DEX-B |
| SAMN31373368 | location_locality | Barcelona | R1 | 0.85 | biosample.attribute:geo_loc_name | Spain: Barcelona |
| SAMN31373368 | sex | male | R1 | 0.90 | sample.attr.host_sex | male |
| SAMN31373368 | subject_id | 10 | R1 | 0.70 | sample.name_rule:alias | 10_DEX-B |
Sequencing
80 runs over 80 samples · mean 12.34 Gbp per run (median 12.20 Gbp, total 986.97 Gbp; 80 runs with a base count) · layout PAIRED 80 · platform ILLUMINA 80 · models NextSeq 500 (80) · 92% of runs with a Sandpiper profile · first public 2023-04-28 – 2023-05-05
Authors (10)
Barber C first · Sabater C · Ávila-Gálvez M · Vallejo F · Bendezu RA · Guérin-Deremaux L · Guarner F · Espín JC · Margolles A · Azpiroz F last
Downloads
PRJNA892265.csv.gz (2.8 KB) · parquet (73.0 KB) — all 80 samples, every field with route and confidence · PRJNA892265_determinations.csv.gz (5.5 KB) — 633 evidence rows