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PRJNA893901 SRP404646

Gut metagenomes in IBD vs healthy controls, Kazan, Russia

MEDIC Challenge test sequencing data

Case-control study of 3 gut metagenome samples from Kazan, Russia, comparing a healthy control, a Crohn's disease patient, and an ulcerative colitis patient. machine-written summary

100 samples · 105 runs · RU · Age unknown · 2023 · 4.08 Gbp / sample

Sources
○Sequence archive✓Abstract / description 100✓Full text 200○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
○ Sequence archiverecords read; no usable sample values
✓ Abstract / description100 sample values (health condition detail)
✓ Full text200 sample values (country, location site) · PMC10113391
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown100
Country
RU100
Body site
primary100
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)this project, 1–3 Gbp: 2 samplesall projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 96 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)this project, 10–30 Gbp: 2 samplesall projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 4.08 Gbp per sample0130Gbp
Community composition
Prevotella 8.3%Faecalibacterium 6.7%Roseburia 4.6%Bifidobacterium 3.8%Bacteroides 3.2%Blautia_A 3.1%Streptococcus 3.0%Phocaeicola 2.9%Fimenecus 2.5%Vescimonas 2.2%Gemmiger 1.9%Dialister 1.7%not assigned to a genus 8.9%other genera 47.3%

Genera, mean relative abundance over 3 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country100 100%100
health_condition0 0%
subject_id0 0%
detailed_location100 100%
health_condition_detail100 100%100
location_site100 100%100
Papers (1)
  • Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge. 2023 PMID 37072468 PMC10113391 own_data
Details
Archive description

WGS gut metagenome of healthy individuals and IBD patients used for benchmarking MEDIC challenge

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.65. Assay shotgun_dna.

  • host run.host_tax_id · “9606”
  • body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SRR22050084countryRUR30.70paper.fulltext.methodsindividuals living in the republic of Tatarstan
SRR22050084health_condition_detailmixed_case_control: Study includes both IBD patients (Ulcerative Colitis and Crohn's Disease) and non-IBD controlsR40.50paper.abstractIBD and nonIBD subjects
SRR22050084location_siteKazan Federal UniversityR30.70paper.fulltext.methodsethics committee of the Kazan Federal University, Kazan, Russia
Sequencing

105 runs over 100 samples · mean 4.14 Gbp per run (median 4.08 Gbp, total 434.95 Gbp; 105 runs with a base count) · layout PAIRED 105 · platform ILLUMINA 105 · models Illumina MiSeq (105) · 89% of runs with a Sandpiper profile · first public 2023-04-14

Authors (26)

Khachatryan L first · Xiang Y · Ivanov A · Glaab E · Graham G · Granata I · Giordano M · Maddalena L · Piccirillo M · Manipur I · Baruzzo G · Cappellato M · Avot B · Stan A · Battey J · Lo Sasso G · Boue S · Ivanov NV · Peitsch MC · Hoeng J · Falquet L · Di Camillo B · Guarracino MR · Ulyantsev V · Sierro N · Poussin C last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA893901.csv.gz (3.1 KB) · parquet (72.8 KB) — all 100 samples, every field with route and confidence · PRJNA893901_determinations.csv.gz (1.9 KB) — 300 evidence rows

Samples (100 · every field this project has values for · hover a cell for its source)
Loading the sample table…