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PRJNA902178 SRP408198

Gut microbiome in allergic individuals, China, intervention

Effects of Lacticaseibacillus paracasei PC-01 on gut microbes in people with allergies

150 fecal samples from China, studied in an intervention design examining gut microbiota in relation to allergy, with the paper's companion analysis linking fecal proline levels to serum IgE and allergic status. machine-written summary

150 samples · 150 runs · CN · Age unknown · 2022 · 6.67 Gbp / sample

Sources
✓Sequence archive 300○Abstract / description✓Full text 150○Supplementary tables–External resources–User contribution–Human verified

Checked this project's papers and archive records yourself? Mark it human-verified.

what each source gave
✓ Sequence archive300 sample values (collection date, country)
○ Abstract / descriptionread; no usable statement
✓ Full text150 sample values (location site) · PMC9748422
○ Supplementary tablesfiles read; no table could be matched to the samples
– External resourcesnot covered by the external resources we ingest
– User contributionnothing uploaded yet · share metadata
– Human verifiednot yet checked by a person · I checked this project — verify it
Samples at a glance
1 country
Age
unknown150
Country
CN150
Body site
primary150
Sequencing depth per sample · this project all projects
all projects, 0–0.03 Gbp: 25,080 samples (4 %)all projects, 0.03–0.1 Gbp: 17,066 samples (3 %)all projects, 0.1–0.3 Gbp: 29,179 samples (5 %)all projects, 0.3–1 Gbp: 47,044 samples (8 %)all projects, 1–3 Gbp: 124,983 samples (22 %)all projects, 3–10 Gbp: 253,728 samples (44 %)this project, 3–10 Gbp: 150 samplesall projects, 10–30 Gbp: 72,533 samples (13 %)all projects, 30–100 Gbp: 3,024 samples (1 %)all projects, 100–300 Gbp: 106 samples (0 %)all projects, ≥ 300 Gbp: 9 samples (0 %)project median 6.67 Gbp per sample0130Gbp
Community composition

No Sandpiper profile for this project's samples yet.

Field coverage
fieldsamplescoverageR1R2R3R4
age_category0 0%
country150 100%150
health_condition0 0%
subject_id0 0%
collection_date150 100%150
detailed_location150 100%
location_site150 100%150
Papers (1)
  • Intestinal proline is a potential anti-allergy factor for allergy diagnosis and therapy. 2022 PMID 36532514 PMC9748422 own_data
Details
Archive description

Study the effect of paracasei PC-01 on the intestinal microbiome of allergic people and explore the mechanism of alleviating allergies

How this project entered the registry

Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.70. Assay shotgun_dna.

  • host study.title · “gut microbes in people with allergies”
  • body site study.description · “intestinal microbiome of allergic people”
Evidence examples (one per field × route)
samplefieldvaluerouteconf.sourcequote
SAMN31566496collection_date2020-09-21R10.90biosample.attribute:collection_date2020-09-21
SAMN31566496countryCNR10.90sample.attr.geo_loc_nameChina
SAMN31566496location_siteZhejiang Gongshang UniversityR30.70paper.fulltext.methodsmedical office of Zhejiang Gongshang University
Sequencing

150 runs over 150 samples · mean 6.63 Gbp per run (median 6.67 Gbp, total 994.82 Gbp; 150 runs with a base count) · layout PAIRED 150 · platform ILLUMINA 150 · models Illumina NovaSeq 6000 (150) · 93% of runs with a Sandpiper profile · first public 2022-11-20

Authors (10)

Ma J first · Wang C · Wang F · Zhang Y · Liu Y · Zhang J · Gao Z · Xie H · Wang Y · Fu L last

Help complete this project

3 of the 4 core fields are below 50% coverage: age_category, health_condition, subject_id. Share metadata

Downloads

PRJNA902178.csv.gz (4.1 KB) · parquet (74.7 KB) — all 150 samples, every field with route and confidence · PRJNA902178_determinations.csv.gz (2.6 KB) — 450 evidence rows

Samples (150 · every field this project has values for · hover a cell for its source)
Loading the sample table…