Guar gum fibre intervention in healthy adults, Barcelona
22 fecal metagenome samples from healthy adult men in Barcelona, Spain, in a single-arm intervention study testing guar gum (prebiotic fibre) consumption effects on gut microbiota. machine-written summary
22 samples · 22 runs · ES · Age unknown · 2023 · 6.16 Gbp / sample
Checked this project's papers and archive records yourself? Mark it human-verified.
what each source gave
| ✓ Sequence archive | 132 sample values (collection date, country, location locality, sex, subject id, timepoint) |
| ✓ Abstract / description | 44 sample values (health condition, health condition detail) |
| ○ Full text | read; no usable statement or table · PMC10349393 |
| ○ Supplementary tables | files read; no table could be matched to the samples |
| – External resources | not covered by the external resources we ingest |
| – User contribution | nothing uploaded yet |
| – Human verified | not yet checked by a person · I checked this project — verify it |
intervention — arms not resolved
Prebiotic / dietary fibre supplement design single_arm_before_after · population healthy_control · Guar gum 8 g/day for 18 days, single arm
“administered gum guar (8 g/day) for 18 days” — abstract:37457982 (study level; per-sample arms are in the intervention column below)
longitudinal
10 of 12 people sampled more than once (20 samples; median 2, up to 2 per person) · follow-up median 22 d (max 22 d) · median interval between samples 22 d (time from visit codes mapped to the stated schedule). Schedule stated by the source: “stool on day -4 (pre-administration) and day 18 (late administration)” (time origin: intervention_start).
Each row is one person (10 shown); dots are samples at days since that person's first sample.
Genera, mean relative abundance over 19 profiled gut samples of this project (Sandpiper SingleM profiles, GTDB R232; low-depth and non-metagenome profiles left out).
| field | samples | coverage | R1 | R2 | R3 | R4 |
|---|---|---|---|---|---|---|
| age_category | 22 | 100% | ||||
| country | 22 | 100% | 22 | |||
| health_condition | 22 | 100% | 22 | |||
| subject_id | 22 | 100% | 22 | |||
| collection_date | 22 | 100% | 22 | |||
| detailed_location | 22 | 100% | ||||
| health_condition_detail | 22 | 100% | 22 | |||
| location_locality | 22 | 100% | 22 | |||
| sex | 22 | 100% | 22 | |||
| timepoint_label | 22 | 100% | 22 |
- Metabolic response of intestinal microbiota to guar gum consumption. 2023 PMID 37457982 PMC10349393 own_data
Archive description
Shotgun metagenomics sequencing data for the article "Metabolic response of intestinal microbiota to guar guam consumption"
How this project entered the registry
Classified as human gut / stool shotgun DNA metagenome of age unknown by sonnet_x2 with confidence 0.68. Assay shotgun_dna.
- host run.host_tax_id · “9606”
- body site run.scientific_name · “human gut metagenome”
Evidence examples (one per field × route)
| sample | field | value | route | conf. | source | quote |
|---|---|---|---|---|---|---|
| SAMN31898194 | collection_date | 2022-05-26 | R1 | 0.90 | biosample.attribute:collection_date | 2022-05-26 |
| SAMN31898194 | country | ES | R1 | 0.90 | sample.attr.geo_loc_name | Spain: Barcelona |
| SAMN31898194 | health_condition | healthy_control | R4 | 0.50 | paper.abstract | Healthy male subjects ( n = 12) |
| SAMN31898194 | health_condition_detail | All subjects described as healthy | R4 | 0.50 | paper.abstract | Healthy male subjects ( n = 12) |
| SAMN31898194 | location_locality | Barcelona | R1 | 0.85 | biosample.attribute:geo_loc_name | Spain: Barcelona |
| SAMN31898194 | sex | male | R1 | 0.90 | sample.attr.host_sex | male |
| SAMN31898194 | subject_id | 1 | R1 | 0.70 | sample.name_rule:alias | 1HPRE |
| SAMN31898194 | timepoint_label | PRE | R1 | 0.70 | sample.name_rule:alias | 1HPRE |
Sequencing
22 runs over 22 samples · mean 6.41 Gbp per run (median 6.16 Gbp, total 140.92 Gbp; 22 runs with a base count) · layout PAIRED 22 · platform ILLUMINA 22 · models NextSeq 500 (22) · 86% of runs with a Sandpiper profile · first public 2023-06-22 – 2023-06-23
Authors (5)
Barber C first · Sabater C · Guarner F · Margolles A · Azpiroz F last
Downloads
PRJNA906167.csv.gz (1.5 KB) · parquet (70.7 KB) — all 22 samples, every field with route and confidence · PRJNA906167_determinations.csv.gz (1.9 KB) — 176 evidence rows